Protein Alignment CG34458 and PLG

DIOPT Version :10

• Sequence 1: NP_001097340.1
• Gene: CG34458 / 5740868
• FlyBaseID: FBgn0085487
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_000292.1
• Gene: PLG / 5340
• HGNCID: 9071
• Length: 810
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 82/235 - (34%)
• Similarity: 113/235 - (48%)
• Gaps: 23/235 - (9%)

  Fly    31 RIIGGQFAAPGQFPHQVSLQLN-GRHHCGGSLISDTMIVTAAHC-TMGQNPGQMKAIVGTN---D 90
            |::||..|.|..:|.||||:.. |.|.|||:|||...::||||| .....|...|.|:|.:   :
Human   580 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVN 644

  Fly    91 LSAGNGQTFNIAQFIIHPRYNPQSQDFDMSLIKLSSPVPMGGAVQTIQLADSDSNYAADTMAMIS 155
            |.. :.|...:::..:.|...      |::|:|||||..:...|....|...:...|..|...|:
Human   645 LEP-HVQEIEVSRLFLEPTRK------DIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFIT 702

  Fly   156 GFGAINQNLQLPNRLKFAQVQLWSRDYCNSQNIPGLTDRM----VCAGHPSGQVSSCQGDSGGPL 216
            |:|. .|.......||.||:.:.....||....  |..|:    :||||.:|...||||||||||
Human   703 GWGE-TQGTFGAGLLKEAQLPVIENKVCNRYEF--LNGRVQSTELCAGHLAGGTDSCQGDSGGPL 764

  Fly   217 TVDGK----LFGVVSWGFGCGAKGRPAMYTYVGALRSWIK 252
            ....|    |.||.|||.||....:|.:|..|....:||:
Human   765 VCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIE 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34458	NP_001097340.1	Tryp_SPc	32..254	CDD:238113	81/234 (35%)
PLG	NP_000292.1	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..145
		KR	183..263	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..416
		KR	479..560	CDD:214527
		Tryp_SPc	581..804	CDD:238113	80/232 (34%)