Protein Alignment CG34458 and KLK12

DIOPT Version :10

• Sequence 1: NP_001097340.1
• Gene: CG34458 / 5740868
• FlyBaseID: FBgn0085487
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 86/256 - (33%)
• Similarity: 116/256 - (45%)
• Gaps: 27/256 - (10%)

  Fly    10 LSILLLAVTFVHSDMDVAEESRIIGGQFAAPGQFPHQVSLQLNGRHHCGGSLISDTMIVTAAHCT 74
            |||.||....   .:..|...:|..|........|.||.|.......|||.||....::|||||:
Human     3 LSIFLLLCVL---GLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCS 64

  Fly    75 MGQNPGQMKAI-VGTNDLSA--GNGQTFNIAQFIIHPRY--NPQSQDFDMSLIKLSSPVPMGGAV 134
                 |....: :|.:.||.  ...|..:....:.||.|  ...|.:.|:.|::|..||.:..:|
Human    65 -----GSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSV 124

  Fly   135 QTIQLADSDSNYAADTMAMISGFGAINQ-NLQLPNRLKFAQVQLWSRDYCNSQNIPG-LTDRMVC 197
            |.:.|.:..:  .|.|...:||:|..|. ....|:.|:...:.:.|...|:.. .|| :|..|||
Human   125 QPLPLPNDCA--TAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGV-YPGRITSNMVC 186

  Fly   198 AGHPSGQVSSCQGDSGGPLTVDGKLFGVVSWGF--GCGAKGRPAMYTY------VGALRSW 250
            ||...|| .:|||||||||...|.|.|:||||.  .||..|.|.:|||      ||...||
Human   187 AGGVPGQ-DACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICNSTLVGLGTSW 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34458	NP_001097340.1	Tryp_SPc	32..254	CDD:238113	80/234 (34%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	76/222 (34%)