Protein Alignment CG34458 and KLK1

DIOPT Version :10

• Sequence 1: NP_001097340.1
• Gene: CG34458 / 5740868
• FlyBaseID: FBgn0085487
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 78/264 - (29%)
• Similarity: 122/264 - (46%)
• Gaps: 36/264 - (13%)

  Fly    12 ILLLAVTFVHSDMDVAEESRIIGGQFAAPGQFPHQVSLQLNGRHHCGGSLISDTMIVTAAHCTMG 76
            :|.||::...:......:|||:||........|.|.:|.......|||.|:....::|||||
Human     5 VLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHC--- 66

  Fly    77 QNPGQMKAIVGTNDLSAGNGQTF---NIAQFI------IHPRYN---------PQSQDF--DMSL 121
                    |.....|..|....|   |.|||:      .||.:|         ...:|:  |:.|
Human    67 --------ISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLML 123

  Fly   122 IKLSSPV-PMGGAVQTIQLADSDSNYAADTMAMISGFGAIN-QNLQLPNRLKFAQVQLWSRDYCN 184
            ::|:.|. .:..||:.::|...:....:..:|  ||:|:|. :|...|:.|:...:::...|.|.
Human   124 LRLTEPADTITDAVKVVELPTEEPEVGSTCLA--SGWGSIEPENFSFPDDLQCVDLKILPNDECK 186

  Fly   185 SQNIPGLTDRMVCAGHPSGQVSSCQGDSGGPLTVDGKLFGVVSWGF-GCGAKGRPAMYTYVGALR 248
            ..::..:||.|:|.||..|...:|.|||||||..||.|.||.|||: .||...:|::...|.:..
Human   187 KAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYV 251

  Fly   249 SWIK 252
            .||:
Human   252 KWIE 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34458	NP_001097340.1	Tryp_SPc	32..254	CDD:238113	73/244 (30%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	73/244 (30%)