DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34458 and TMPRSS9

DIOPT Version :10

Sequence 1:NP_001097340.1 Gene:CG34458 / 5740868 FlyBaseID:FBgn0085487 Length:257 Species:Drosophila melanogaster
Sequence 2:NP_001382442.1 Gene:TMPRSS9 / 360200 HGNCID:30079 Length:1093 Species:Homo sapiens


Alignment Length:230 Identity:95/230 - (41%)
Similarity:134/230 - (58%) Gaps:9/230 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 RIIGGQFAAPGQFPHQVSLQLNGRHHCGGSLISDTMIVTAAHC-TMGQNPGQMKAIVGTNDLSAG 94
            ||:||..|:||:||.|.||:.|..|.||.::|:...:|:|||| ...|:|.:..|.||...||..
Human   236 RIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGATYLSGS 300

  Fly    95 NGQTF--NIAQFIIHPRYNPQSQDFDMSLIKLSSPVPMGGAVQTIQLADSDSNYAADTMAMISGF 157
            ...|.  .:.|.:.||.||..:.|||:::::|:||:|.|..:|.:.|..:...:......:|||:
Human   301 EASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSKKCLISGW 365

  Fly   158 GAINQN-LQLPNRLKFAQVQLWSRDYCNSQNIPGLTDRMVCAGHPSGQVSSCQGDSGGPLTVD-- 219
            |.:.:: |..|..|:.|.|:|..:..|.|.....|||||||||:..|:|.||||||||||..:  
Human   366 GYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEEP 430

  Fly   220 -GKLF--GVVSWGFGCGAKGRPAMYTYVGALRSWI 251
             |:.|  |:||||.||....||.:|..|..||.||
Human   431 SGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWI 465

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34458NP_001097340.1 Tryp_SPc 32..254 CDD:238113 94/229 (41%)
TMPRSS9NP_001382442.1 SEA 66..>127 CDD:460188
LDLa 188..223 CDD:238060
Tryp_SPc 236..465 CDD:214473 93/228 (41%)
Tryp_SPc 538..768 CDD:238113
Pneumo_att_G <717..>867 CDD:114270
Tryp_SPc 861..1087 CDD:238113
Blue background indicates that the domain is not in the aligned region.

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