Protein Alignment CG34458 and KLK3

DIOPT Version :10

• Sequence 1: NP_001097340.1
• Gene: CG34458 / 5740868
• FlyBaseID: FBgn0085487
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 82/260 - (31%)
• Similarity: 124/260 - (47%)
• Gaps: 23/260 - (8%)

  Fly     8 VKLSILLLAVTFVHSDMDVAEESRIIGGQFAAPGQFPHQVSLQLNGRHHCGGSLISDTMIVTAAH 72
            |.:..|.|:||::.:...:.  |||:||........|.||.:...||..|||.|:....::||||
Human     3 VPVVFLTLSVTWIGAAPLIL--SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65

  Fly    73 CTMGQNPGQMKAIVGTNDL--SAGNGQTFNIAQFIIHPRYN-----------PQSQDFDMSLIKL 124
            |...::    ..::|.:.|  ....||.|.::....||.|:           ......|:.|::|
Human    66 CIRNKS----VILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRL 126

  Fly   125 SSPVPMGGAVQTIQLADSDSNYAADTMAMISGFGAIN-QNLQLPNRLKFAQVQLWSRDYCNSQNI 188
            |.|..:..||:.:.|...:.  |..|....||:|:|. :....|.:|:...:.:.|.|.|...:.
Human   127 SEPAELTDAVKVMDLPTQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP 189

  Fly   189 PGLTDRMVCAGHPSGQVSSCQGDSGGPLTVDGKLFGVVSWGF-GCGAKGRPAMYTYVGALRSWIK 252
            ..:|..|:|||..:|..|:|.|||||||..:|.|.|:.|||. .|....||::||.|...|.|||
Human   190 QKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 254

  Fly   253  252
            Human   255  254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34458	NP_001097340.1	Tryp_SPc	32..254	CDD:238113	75/236 (32%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	75/236 (32%)