Protein Alignment CG34458 and KLK5

DIOPT Version :10

• Sequence 1: NP_001097340.1
• Gene: CG34458 / 5740868
• FlyBaseID: FBgn0085487
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 80/279 - (28%)
• Similarity: 121/279 - (43%)
• Gaps: 42/279 - (15%)

  Fly    10 LSILLLAVT-FVHSDMDVA----------------------------EESRIIGGQFAAPGQFPH 45
            ::.|||.|| .|.::.||:                            ..||||.|........|.
Human    16 ITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPW 80

  Fly    46 QVSLQLN-GRHHCGGSLISDTMIVTAAHCTMGQNPGQMKAIVGTNDLS---AGNGQTFNIAQFII 106
            |.:|.|. .:.:||..|:....::|||||    .....:..:|...||   ....|.|...:.|.
Human    81 QAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLGHYSLSPVYESGQQMFQGVKSIP 141

  Fly   107 HPRYNPQSQDFDMSLIKLSSPVPMGGAVQTIQLADSDSNYAADTMAMISGFGAI-NQNLQLPNRL 170
            ||.|:......|:.||||:..:.....|:.|.:  |....:|.|..::||:|.. :..:..|..|
Human   142 HPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINV--SSHCPSAGTKCLVSGWGTTKSPQVHFPKVL 204

  Fly   171 KFAQVQLWSRDYCNSQNIPGLTDRMVCAGHPSGQVSSCQGDSGGPLTVDGKLFGVVSWG-FGCGA 234
            :...:.:.|:..|.......:.|.|.|||..:|: .|||||||||:..:|.|.|:|||| :.|..
Human   205 QCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGR-DSCQGDSGGPVVCNGSLQGLVSWGDYPCAR 268

  Fly   235 KGRPAMYTYVGALRSWIKQ 253
            ..||.:||.:.....||::
Human   269 PNRPGVYTNLCKFTKWIQE 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34458	NP_001097340.1	Tryp_SPc	32..254	CDD:238113	70/228 (31%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/30 (7%)
		Tryp_SPc	66..285	CDD:214473	69/225 (31%)