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Protein Alignment CG34458 and TMPRSS6

DIOPT Version :10

Sequence 1:	NP_001097340.1	Gene:	CG34458 / 5740868	FlyBaseID:	FBgn0085487	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001275929.1	Gene:	TMPRSS6 / 164656	HGNCID:	16517	Length:	824	Species:	Homo sapiens

Alignment Length:	268	Identity:	90/268 - (33%)
Similarity:	139/268 - (51%)	Gaps:	37/268 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 HSDMDV-AEESRIIGGQFAAPGQFPHQVSLQLNGRHHCGGSLISDTMIVTAAHCTMGQNPGQMKA 84
            |.|..: ...|||:||..::.|::|.|.|||:.|||.|||:||:|..::|||||.  |.......
Human   556 HCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCF--QEDSMAST 618

  Fly    85 IVGTNDL------SAGNGQ-TFNIAQFIIHPRYNPQSQDFDMSLIKLSSPVPMGGAVQTIQLADS 142
            ::.|..|      |...|: :|.:::.::||.:...|.|:|::|::|..||....||:.:.|...
Human   619 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPAR 683

  Fly   143 DSNYAADTMAMISGFGAI-----------------NQNLQ-----LPNRLKFAQVQLWSRDYCNS 185
            ...:.......|:|:||:                 ||..:     :.|.|:...|||..:|.|:.
Human   684 SHFFEPGLHCWITGWGALREGALRADAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSE 748

  Fly   186 QNIPGLTDRMVCAGHPSGQVSSCQGDSGGPL---TVDGKLF--GVVSWGFGCGAKGRPAMYTYVG 245
            .....:|.||:|||:..|:..:|||||||||   .:.|:.|  |:||||.|||......:||.:.
Human   749 VYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRIT 813

  Fly   246 ALRSWIKQ 253
            .:.|||:|
Human   814 GVISWIQQ 821

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.