Protein Alignment CG34458 and KLK11

DIOPT Version :10

• Sequence 1: NP_001097340.1
• Gene: CG34458 / 5740868
• FlyBaseID: FBgn0085487
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 85/284 - (29%)
• Similarity: 133/284 - (46%)
• Gaps: 53/284 - (18%)

  Fly     7 LVKLSILLLAVTFVHSDMDVAEESRIIGGQFAAPGQFPHQVSLQLNGRHHCGGSLISDTMIVTAA 71
            :::|.:|.||...      |..|:|||.|....|...|.|.:|....|..||.:||:...::|||
Human    35 ILQLILLALATGL------VGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93

  Fly    72 HCTMGQNPGQMKAIVG-------TNDLSAGNGQTFNIAQFIIH-PRYNPQSQD------------ 116
            ||        :|..|.       :.|||:.|....:::::|:| .::|.|.::
Human    94 HC--------LKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESF 150

  Fly   117 ---------------FDMSLIKLSSPVPMGGAVQTIQLADSDSNYAADTMAMISGFGAINQ-NLQ 165
                           .|:.|:|::|||.:..||:.:.|  |.....|.|..:|||:|:.:. .|:
Human   151 PHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTL--SSRCVTAGTSCLISGWGSTSSPQLR 213

  Fly   166 LPNRLKFAQVQLWSRDYCNSQNIPGLTDRMVCAGHPSGQVSSCQGDSGGPLTVDGKLFGVVSWGF 230
            ||:.|:.|.:.:.....|.:.....:||.||||....|...||||||||||..:..|.|::|||.
Human   214 LPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQ 278

  Fly   231 G-CGAKGRPAMYTYVGALRSWIKQ 253
            . |....:|.:||.|.....||::
Human   279 DPCAITRKPGVYTKVCKYVDWIQE 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34458	NP_001097340.1	Tryp_SPc	32..254	CDD:238113	78/259 (30%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	77/256 (30%)