Protein Alignment CG34458 and PRSS21

DIOPT Version :10

• Sequence 1: NP_001097340.1
• Gene: CG34458 / 5740868
• FlyBaseID: FBgn0085487
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 92/282 - (32%)
• Similarity: 135/282 - (47%)
• Gaps: 46/282 - (16%)

  Fly    13 LLLAVTFVHSDMDVAEE----------------SRIIGGQFAAPGQFPHQVSLQLNGRHHCGGSL 61
            ||||:....:.:...|.                |||:||:.|..|::|.|.||:|...|.||.||
Human     7 LLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSL 71

  Fly    62 ISDTMIVTAAHC--TMG--QNP-------GQMKAIVGTNDLSAGNGQTFNIAQFIIHPRYNPQSQ 115
            :|....:|||||  |..  .:|       ||:.::.....|.|...:.| ::...:.|||...|
Human    72 LSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF-VSNIYLSPRYLGNS- 134

  Fly   116 DFDMSLIKLSSPVPMGGAVQTIQLADSDSNYAADTMAMISGFGAINQN--LQLPNRLKFAQVQLW 178
            .:|::|:|||:||.....:|.|.|..|...:...|...::|:|.|.::  |..|:.|:..||.:.
Human   135 PYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAII 199

  Fly   179 SRDYCN--------SQNIPGLTDRMVCAGHPSGQVSSCQGDSGGPLTVDGK----LFGVVSWGFG 231
            :...||        .::|.|   .|||||:..|...:|.|||||||..:..    ..||||||.|
Human   200 NNSMCNHLFLKYSFRKDIFG---DMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVG 261

  Fly   232 CGAKGRPAMYTYVGALRSWIKQ 253
            ||...||.:||.:.....||::
Human   262 CGRPNRPGVYTNISHHFEWIQK 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34458	NP_001097340.1	Tryp_SPc	32..254	CDD:238113	85/247 (34%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	85/245 (35%)