DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34409 and CG6592

DIOPT Version :9

Sequence 1:	NP_001097728.2	Gene:	CG34409 / 5740854	FlyBaseID:	FBgn0085438	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	80/346 - (23%)
Similarity:	138/346 - (39%)	Gaps:	98/346 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 PASLSTTTASMPPFAQENT-----------------QGCG------------------INVES-- 248
            ||.|||:::|  ||:...:                 :|.|                  :|:|:
  Fly    45 PAGLSTSSSS--PFSSSGSLEHDAEMSASNVDNRHIKGLGMGREMSALSEEDDREPLVLNLETTP 107

  Fly   249 --------------RLLGGDQASAGQFPWLTRIAYRNRSSSRISFRCSGSLISSNHIVTAAHCV- 298
                          |:.|||..:...||:...:..:....   .:.|.|||||..|::||||||
  Fly   108 LMEKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQRPKG---LYWCGGSLISDKHVITAAHCVD 169

  Fly   299 --VNLVSDLELSHVRLGSQDGATPFAI--EQVIVHPNYDQPKYANDIALLRINSTNGTFTPICLP 359
              ...:..|..:.::...:.|.....:  |...::|.::..:..:|||::|:        |..:.
  Fly   170 MAKRALVFLGANEIKNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRL--------PHAVS 226

  Fly   360 FN---GPITLGNR------LIGQIGVAAGWSIGSTENNSSMDPSNSTAGVRFIRLPIVNTTSCAI 415
            ||   .||.|..|      ...::.:|:||...:|..::.   ||.   :|:::|.|::..:|
  Fly   227 FNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYATGVHAI---SNV---LRYVQLQIIDGRTC-- 283

  Fly   416 AYASLSENFQQPIVITPNHLCAQGMPMNDVCRGDSGGPFMDDGTSGVFGTSGRYTIIGIVAFGPT 480
                 ..||  |:.....::|..|......|.||||||.:.....     |.:..::||.:||..
  Fly   284 -----KSNF--PLSYRGTNICTSGRNARSTCNGDSGGPLVLQRRH-----SKKRVLVGITSFGSI 336

  Fly   481 LCGVTTIPGVYTLVSSFSDWI 501
            .......|..:|.|:|:.|||
  Fly   337 YGCDRGYPAAFTKVASYLDWI 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34409	NP_001097728.2	CLIP	26..71	CDD:288855
		Tryp_SPc	249..501	CDD:214473	66/265 (25%)
		Tryp_SPc	252..501	CDD:238113	65/262 (25%)
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	66/265 (25%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	67/266 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436423
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	4	3.940