DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34409 and sphinx1

DIOPT Version :9

Sequence 1:	NP_001097728.2	Gene:	CG34409 / 5740854	FlyBaseID:	FBgn0085438	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_729255.2	Gene:	sphinx1 / 318005	FlyBaseID:	FBgn0052383	Length:	253	Species:	Drosophila melanogaster

Alignment Length:	259	Identity:	64/259 - (24%)
Similarity:	101/259 - (38%)	Gaps:	40/259 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 RLLGGDQASAGQFPWLTRIAYRNRSSSRISFRCSGSLISSNHIVTAAHCVVNLVSDLELSHVRLG 313
            |:.||.:|......:|..|.|....:|.:::. :|::||:..|:|     |..|.......|.|.
  Fly    25 RIAGGYRAKTFTIIYLVGIVYFKSQTSSLNYG-AGTIISNQWILT-----VKTVLKYSYIEVHLA 83

  Fly   314 SQDGATPFAIEQVIVHPNYDQPKYAND--IALLR--INSTNGTFTPICLPFNGPITLGNRLIGQI 374
            |:.....|.|  :.::....:..|.||  |||::  ....:.....:.:|...  |...|.:|.:
  Fly    84 SRRSYRGFDI--IRIYKENFRFHYDNDHVIALVKCPYQKFDRRMDRVRVPAYD--TRFERYVGNM 144

  Fly   375 GVAAGWSIGSTENNSSMDPSNSTAGVRFIRLPIVNTTSCAIAYASLSENFQQPIVITPNHLCAQG 439
            .:..|:   .||...:..|.    .:|.|.:.::|.|.||..|..|..          ..:|..|
  Fly   145 TMVCGY---GTEKRHAKLPE----WMRCIEVEVMNNTECAKYYTPLKW----------YEMCTSG 192

  Fly   440 MPMNDVCRGDSGGPFMDDGTSGVFGTSGRYTIIGIVAFGPTLCGVTTIPGVYTLVSSFSDWILR 503
            .....||.||.||..:..|.:..|        |||:...|..|.: ..|.|:..||....||.|
  Fly   193 EGFKGVCEGDIGGAVVTMGPNPTF--------IGIIWLMPENCSI-GYPSVHIRVSDHIKWIKR 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34409	NP_001097728.2	CLIP	26..71	CDD:288855
		Tryp_SPc	249..501	CDD:214473	61/255 (24%)
		Tryp_SPc	252..501	CDD:238113	60/252 (24%)
sphinx1	NP_729255.2	Tryp_SPc	25..245	CDD:214473	61/255 (24%)
sphinx1	NP_729255.2	Tryp_SPc	26..248	CDD:304450	63/258 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436390
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030