Protein Alignment CG17636 and GGT1

DIOPT Version :10

• Sequence 1: NP_001245442.1
• Gene: CG17636 / 5740847
• FlyBaseID: FBgn0025837
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_038265.2
• Gene: GGT1 / 2678
• HGNCID: 4250
• Length: 569
• Species: Homo sapiens
• Alignment Length: 558
• Identity: 227/558 - (40%)
• Similarity: 324/558 - (58%)
• Gaps: 32/558 - (5%)

  Fly    19 KKYAVCWIILVVTALGVTLGLVFGLRSKAEEPRR----IGAVASNGVGCAEVGGSILDIGGSAAD 79
            ||..|..::.||..| |.:||...|.|.::||..    ..|||::...|:::|...|..||||.|
Human     3 KKLVVLGLLAVVLVL-VIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVD 66

  Fly    80 AAIATMLCEGVMLPHSLGVGGGFVATIYSRETEFSEVLIARETAPAAATQDMFVKTEIT--GALS 142
            ||||.:||.|:|..||:|:|||...|||:..|..:||:.|||.||..|...||..:|.:  |.||
Human    67 AAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLS 131

  Fly   143 CAVPAEIYGYSELHDKYGRLPWKTLFQPTIDLCRRGILVSRYLSGVLQREEERIRNEPSMAEIFI 207
            .|||.||.||...|.::|||||..||||:|.|.|:|..|.:.|:..|:.:...|..:|.:.|:|.
Human   132 VAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFC 196

  Fly   208 NPKTDEVYKQGEVMYRHTLAETLEIIADEGAKAIYGGGRVGRKLVEDIQAMGGIVTEEDLQSYNV 272
            ..:  :|.::||.:....||:|.|.:|.|||:|.|.|. :..::|:||||.|||||.|||.:|..
Human   197 RDR--KVLREGERLTLPQLADTYETLAIEGAQAFYNGS-LTAQIVKDIQAAGGIVTAEDLNNYRA 258

  Fly   273 RW-EMPLHSHFSGGYKLITSTLPTSGAVLTFMLNVMEPLYTSNTDKY---------WQRLIETFK 327
            .. |.||:... |...|...:.|.||.||..:||:::. |..:.:..         :.|::|.|:
Human   259 ELIEHPLNISL-GDVVLYMPSAPLSGPVLALILNILKG-YNFSRESVESPEQKGLTYHRIVEAFR 321

  Fly   328 HAYGHRTNLGDIHYEPDVQEMYENLIDPAFAAEIRKLILDDRTFEDMSYYGANFANEEDHGTAHI 392
            .||..||.|||..: .||.|:..|:....|||::|..|.||.| ..:|||...|...:|.||||:
Human   322 FAYAKRTLLGDPKF-VDVTEVVRNMTSEFFAAQLRAQISDDTT-HPISYYKPEFYTPDDGGTAHL 384

  Fly   393 SVLAPNGDAISVTSTINSHLGAKVRSRQTGFILNDEMDDFSTPGKINAYGIPASPANFIKPGKRP 457
            ||:|.:|.|:|.|||||.:.|:||||..:|.:.|:||||||:|...|.:|:|.||||||:|||:|
Human   385 SVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQP 449

  Fly   458 MSSTCPSIVLDTHGNVKLIVGGAGGSKITTSVAQTILRYFVLHEPIEKAVNSGRLHHQLAPMHID 522
            :||.||:|::...|.|:::||.|||::|||:.|..|:........:::||...|||:||.|....
Human   450 LSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTT 514

  Fly   523 MEPNVPRHTVAYLSAIGHDIRFLEDDKAYSAQTAIGIL 560
            :|.|:.:...|.|....|..:.        |.|.|.::
Human   515 VERNIDQAVTAALETRHHHTQI--------ASTFIAVV 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17636	NP_001245442.1	G_glu_transpept	69..574	CDD:425991	209/504 (41%)
GGT1	NP_038265.2	G_glu_transpept	55..564	CDD:425991	209/505 (41%)