Protein Alignment JYalpha and ENA1

DIOPT Version :9

• Sequence 1: NP_001104092.2
• Gene: JYalpha / 5740846
• FlyBaseID: FBgn0267363
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: NP_010325.1
• Gene: ENA1 / 851610
• SGDID: S000002447
• Length: 1091
• Species: Saccharomyces cerevisiae
• Alignment Length: 1139
• Identity: 328/1139 - (28%)
• Similarity: 501/1139 - (43%)
• Gaps: 269/1139 - (23%)

  Fly    33 HKIPVDELLERLKTDPNMGLSFVEAKLRLEINGPNIL------------TPQPPTPKWIVFLKTM 85
            |.:..:|..|.:.|....||:..|...||:..|.|.|            ..|......:|.|.:|
Yeast    18 HTLTAEEAAEFIGTSLTEGLTQDEFVHRLKTVGENTLGDDTKIDYKAMVLHQVCNAMIMVLLISM 82

  Fly    86 FGGFAILLW-AGSFLCFVGYLIQLQTQHEPPDDNLYLGIALTVLVIVTGLFTYFQVHKSSSIMDS 149
            ...||:..| .|..:.||                    ||:.||:   ||   .|.:|::..|:|
Yeast    83 IISFAMHDWITGGVISFV--------------------IAVNVLI---GL---VQEYKATKTMNS 121

  Fly   150 FKNLVPQYATVIREGEINTVTSDEIVKGDIVEVKFGDRVPADIRILEAHGLKVDNSSLTGESEPQ 214
            .|||....|.|||.|:..|:.|.::|.|||..||.||.:|||:|::|......|.|.|||||.|.
Yeast   122 LKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTIPADLRLIETKNFDTDESLLTGESLPV 186

  Fly   215 VRSTEFTHENPLETK-----NLAFFSTNVLEGTCRGVVIATGDSTVMGRIANLAAGLD------- 267
            .:..........||.     ||||.|:.|::|..:|:||.|..::.:|:||....|..
Yeast   187 SKDANLVFGKEEETSVGDRLNLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDP 251

  Fly   268 ----------------------DVQSPISREIQLFIRFITIFAIILGLSFFAISLTLGYEF-ID- 308
                                  :|.:|:.|::......:...|::     |||.:....:| :|
Yeast   252 SKSWLQNTWISTKKVTGAFLGTNVGTPLHRKLSKLAVLLFWIAVL-----FAIIVMASQKFDVDK 311

  Fly   309 -AVVFLIGIIVANVPEGLLVTVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 372
             ..::.|.:.::.:|..|:|.:|:.:::.|..|.|:|.:|:.|:::|.||:.:.|||||||||||
Yeast   312 RVAIYAICVALSMIPSSLVVVLTITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQ 376

  Fly   373 NRMTVAHLWYDQI--IVESDTTESFRG----------------SH-----------FK------- 401
            .:|....:|..:.  |..|::.:.|..                ||           ||
Yeast   377 GKMLARQIWIPRFGTITISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKD 441

  Fly   402 ----IEDKSFNALFMCAALCNSAE-FKGGQDD------------IPVF--KKDVNGNA------- 440
                |:...|......|.|.|.|. ||....|            |.||  |.|:..||
Yeast   442 LPEDIDMDLFQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKST 506

  Fly   441 ------SEAALLKFTETIFAGIGAFRQKHIKLTEIPFNSTEKYQVSVHEFNSSDGYFIVEMKGAP 499
                  .:::|.:..|.    .|:.:.:||  .|.||:||.|...||:..|.::.|.|.. |||.
Yeast   507 NQSNENDQSSLSQHNEK----PGSAQFEHI--AEFPFDSTVKRMSSVYYNNHNETYNIYG-KGAF 564

  Fly   500 ERILDRCSTIIIQGLSVELTPTLKLEFE---EAYLEMGGMGERVLGFADLLLPMSKYPISYEFSA 561
            |.|:..||:...:. .|::||....:.|   :....:...|.||||||           |..|:.
Yeast   565 ESIISCCSSWYGKD-GVKITPLTDCDVETIRKNVYSLSNEGLRVLGFA-----------SKSFTK 617

  Fly   562 DPPN-FPLEN-----------LRFLGLISLIDPPRAAVPDAVAKCRSAGVRVIMVTGDHPITAKA 614
            |..| ..|:|           |.|||||.:.||||.....||.|...||:.|.|:|||...||||
Yeast   618 DQVNDDQLKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKA 682

  Fly   615 IARSVGIITTPT---AEDIAKQRGVTVLDIDSRQATAIVVHGGELREMKAEELDAVIYYHNEIVF 676
            ||:.|||:.|..   :::|          :||     :|:.|.:...:..||:|.:...  .:|.
Yeast   683 IAQEVGILPTNLYHYSQEI----------VDS-----MVMTGSQFDGLSEEEVDDLPVL--PLVI 730

  Fly   677 ARTSPQQKLIIVEACQRRGEIVAVTGDGVNDSPALKRADIGVAMGISGSDVSKQAADMILLDDNF 741
            ||.|||.|:.::||..||.:...:|||||||||:||.|::|:||||:||||||:|:|::|.||||
Yeast   731 ARCSPQTKVRMIEALHRRKKFCTMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNF 795

  Fly   742 ASIVVGIEEGRIIFDNLKKSIAYTLTSNLPEIVPFLFFVIFD-------IPLALGTIAILCIDIG 799
            |||:..:||||.:.||::|.:...|..|:.:.:..:..::|.       .||:  .:.:|.|.:.
Yeast   796 ASILNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLS--PVEVLWIIVV 858

  Fly   800 TDMLPAISLAYEKAESDIMARMPRDPFEDRLVNKKLIL--MAYLQIGVIQTVACFFTFFAIMAEH 862
            |...||:.|..|||..|:|.|.|.|. |..:...::|:  .||   |:|.|.:|..:|...:  :
Yeast   859 TSCFPAMGLGLEKAAPDLMDRPPHDS-EVGIFTWEVIIDTFAY---GIIMTGSCMASFTGSL--Y 917

  Fly   863 GFPPSRLKGIREDWDSKNVEDLEDGYGQEWTYRERKVLEYTAGTGFFVS------IVVTQVFDLL 921
            |....||                 |:..:.||.......|.:.:..|.:      |:..:|.|:
Yeast   918 GINSGRL-----------------GHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDM- 964

  Fly   922 ICKTRRN-------------SILQQGMGNHVLNFALVLEFIIACLLCYVPVF-EKTLRMYSIKFI 972
                ||:             ...:...||..|.::::..|:.|..:.|:||. :|......|...
Yeast   965 ----RRSFFRMHPDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAE 1025

  Fly   973 W-----WIYAFPFGLLIFFFDESRRFLIRR--NP 999
            |     :..||..|..::...:.|.|..:|  ||
Yeast  1026 WGLAIAFTIAFWIGAELYKCGKRRYFKTQRAHNP 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JYalpha	NP_001104092.2	ATPase-IIC_X-K	17..1009	CDD:273445	328/1139 (29%)
		Cation_ATPase_N	29..102	CDD:214842	20/81 (25%)
		E1-E2_ATPase	123..354	CDD:278548	78/267 (29%)
		Cation_ATPase	416..509	CDD:289987	36/120 (30%)
		COG4087	<673..738	CDD:226572	37/64 (58%)
		Cation_ATPase_C	785..994	CDD:279079	53/235 (23%)
ENA1	NP_010325.1	ATPase-IID_K-Na	11..1055	CDD:130586	325/1133 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	70	1.000	Domainoid score	I2260
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920