Protein Alignment JYalpha and ATP2B2

DIOPT Version :9

• Sequence 1: NP_001104092.2
• Gene: JYalpha / 5740846
• FlyBaseID: FBgn0267363
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: XP_016861981.1
• Gene: ATP2B2 / 491
• HGNCID: 815
• Length: 1272
• Species: Homo sapiens
• Alignment Length: 1032
• Identity: 276/1032 - (26%)
• Similarity: 424/1032 - (41%)
• Gaps: 291/1032 - (28%)

  Fly    11 KINGKEKKKDIQSFKKDVETDNHKIPVDELLERLKTDPNMGL--SFVEAKLRLEINGPNILTPQP 73
            ::.|.|....|:....|.|.         :..||||.|..||  :..:.:.|.:|.|.|.:.|:.
Human    36 ELRGTEAVVKIKETYGDTEA---------ICRRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKK 91

  Fly    74 PTPKWIVFLKTMFGGFAILLWAG-----SFLCFVGYLIQ--LQTQHEPPDDN------------- 118
            |        ||    |..|:|..     ..:..:..:|.  |...|.|.:.|
Human    92 P--------KT----FLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQGGAEDE 144

  Fly   119 ------LYLGIALTVLVIVTGLFTYFQVHKSSSIMDSFKNLVPQYA--TVIREGEINTVTSDEIV 175
                  ...|.|:.:.||...|.|.|............::.:.|..  ||:|.|::..:...|||
Human   145 GEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIV 209

  Fly   176 KGDIVEVKFGDRVPADIRILEAHGLKVDNSSLTGESEPQVRSTEFTHENPLETKNLAFFSTNVLE 240
            .|||.:||:||.:|||...::.:.||:|.|||||||: |||.:       ::...:....|:|:|
Human   210 VGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESD-QVRKS-------VDKDPMLLSGTHVME 266

  Fly   241 GTCRGVVIATGDSTVMGRIANL--AAGL-------------DDVQSPIS---------------- 274
            |:.|.:|.|.|.::..|.|..|  |.|.             |.:|.|.:
Human   267 GSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGVKKGDGLQLPAADGAAASNAADSANASL 331

  Fly   275 -------------------------------------------------REIQLFIRFITIFAII 290
                                                             :|..:....:|..|:.
Human   332 VNGKMQDGNVDASQSKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQ 396

  Fly   291 LG-----LSFFAISLTLGYEFIDAVV---------------------FLIG--IIVANVPEGLLV 327
            :|     :|...:.:.:.|..:|..|                     |:||  ::|..|||||.:
Human   397 IGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPL 461

  Fly   328 TVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWYDQIIVESDTT 392
            .||:.|..:.|:|...|.||::|:|.||:|:.:.||||||||||.|||||...:...:
Human   462 AVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDV------- 519

  Fly   393 ESFRGSHFK-------IEDKSFNALFMCAALCNSA--------EFKGGQDDIPVFKKDVNGNASE 442
                  |:|       |..|:...|....|: |||        |.:|.   :|   :.| ||.:|
Human   520 ------HYKEIPDPSSINTKTMELLINAIAI-NSAYTTKILPPEKEGA---LP---RQV-GNKTE 570

  Fly   443 AALLKFTETIFAGIGAFRQK--HIKLTEI-PFNSTEKYQVSVHEFNSSDGYFIVEMKGAPERILD 504
            ..||.|...:.......|.:  ..||.:: .|||..|...:|  ....|..|.:..|||.|.:|.
Human   571 CGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTV--IKLPDESFRMYSKGASEIVLK 633

  Fly   505 RCSTIIIQGLSVELTPTLKLEFEEAYLEMGGMGE-RVL-------------------GFADLLLP 549
            :|..|                       :.|.|| ||.                   |...:.:.
Human   634 KCCKI-----------------------LNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVA 675

  Fly   550 MSKYPISYEFSADPPNFPLENLRFLGLISLIDPPRAAVPDAVAKCRSAGVRVIMVTGDHPITAKA 614
            ...:|.|.|...|..|..|..|..:.::.:.||.|..||:|:.||:.||:.|.|||||:..||:|
Human   676 YRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARA 740

  Fly   615 IARSVGIITTPTAEDIAKQRGVTVLDIDSRQATAIVVHGGELREMKAEELDAVIYYHNEIVFART 679
            ||...|||          ..|...|.::.::....:  ..|..|::.|.:|.:  :....|.||:
Human   741 IAIKCGII----------HPGEDFLCLEGKEFNRRI--RNEKGEIEQERIDKI--WPKLRVLARS 791

  Fly   680 SPQQKLIIVEAC-------QRRGEIVAVTGDGVNDSPALKRADIGVAMGISGSDVSKQAADMILL 737
            ||..|..:|:..       ||  ::|||||||.||.||||:||:|.||||:|:||:|:|:|:||.
Human   792 SPTDKHTLVKGIIDSTHTEQR--QVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILT 854

  Fly   738 DDNFASIVVGIEEGRIIFDNLKKSIAYTLTSNLPEIVPFLFFVIF-------DIPLALGTIAILC 795
            ||||:|||..:..||.::|::.|.:.:.||.|:..::     |.|       |.||.  .:.:|.
Human   855 DDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVI-----VAFTGACITQDSPLK--AVQMLW 912

  Fly   796 IDIGTDMLPAISLAYEKAESDIMARMP---RDPFEDRLVNKKLILMAYLQIGVIQTV 849
            :::..|...:::||.|.....::.|.|   ..|...|.:.|.::..|..|:.:|.|:
Human   913 VNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTL 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JYalpha	NP_001104092.2	ATPase-IIC_X-K	17..1009	CDD:273445	274/1026 (27%)
		Cation_ATPase_N	29..102	CDD:214842	19/79 (24%)
		E1-E2_ATPase	123..354	CDD:278548	80/340 (24%)
		Cation_ATPase	416..509	CDD:289987	29/103 (28%)
		COG4087	<673..738	CDD:226572	37/71 (52%)
		Cation_ATPase_C	785..994	CDD:279079	16/68 (24%)
ATP2B2	XP_016861981.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920