Protein Alignment JYalpha and Atp2b4

DIOPT Version :9

• Sequence 1: NP_001104092.2
• Gene: JYalpha / 5740846
• FlyBaseID: FBgn0267363
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: XP_011246340.1
• Gene: Atp2b4 / 381290
• MGIID: 88111
• Length: 1239
• Species: Mus musculus
• Alignment Length: 1109
• Identity: 302/1109 - (27%)
• Similarity: 478/1109 - (43%)
• Gaps: 284/1109 - (25%)

  Fly    37 VDELLERLKTDPNMGLSFVEAKL--RLEINGPNILTPQPPTPKWIVFLKTMFGGF---------- 89
            |.|:..||||.|..|||...|.|  |..:.|.|::.|:.|.    .||:.::...
Mouse    51 VQEICTRLKTSPIEGLSGNPADLEKRRLVFGKNVIPPKRPK----TFLELVWEALQDVTLIILEI 111

  Fly    90 -AILLWAGSF---------LCFVGYLIQLQTQHEPPDDNLYLGIALTVLVIVTGLFTYFQVHKSS 144
             ||:....||         :|  |::.....:.|..:.....|.|:...||:..|.|.|   ...
Mouse   112 AAIISLVLSFYRPPGGDNEIC--GHIASSPEEEEEGETGWIEGAAILASVIIVVLVTAF---NDW 171

  Fly   145 SIMDSFKNL-----VPQYATVIREGEINTVTSDEIVKGDIVEVKFGDRVPADIRILEAHGLKVDN 204
            |....|:.|     :.|..::||.|::..:...|||.|||.::|:||.:|||..:::.:.||:|.
Mouse   172 SKEKQFRGLQSRIELEQKFSIIRNGQLIQLPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDE 236

  Fly   205 SSLTGESEPQVRSTEFTHENPLETKNLAFFSTNVLEGTCRGVVIATGDSTVMGRI---------- 259
            |||||||: .|:.|       |:...:....|:|:||:.|.||.|.|.::..|.|
Mouse   237 SSLTGESD-HVKKT-------LDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGASEEE 293

  Fly   260 ---------------------------------ANLAAGLD--DVQSPISR----EIQLFIRFIT 285
                                             .|...|||  |.:..|:|    |..:....:|
Mouse   294 DDDDKKKKGKKQGAPENRNKAKTQDGVALEIQPLNSQEGLDSEDKEKKIARIPKKEKSVLQGKLT 358

  Fly   286 IFAIILG-----LSFFAISLTLGYEFIDAVV---------------------FLIG--IIVANVP 322
            ..|:.:|     :|...:.:.:.|..:|..|                     |:||  ::|..||
Mouse   359 RLAVQIGKAGLIMSVLTVVILILYFVVDNFVIQRREWLPECTPVYIQYFVKFFIIGVTVLVVAVP 423

  Fly   323 EGLLVTVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWYDQIIV 387
            |||.:.||:.|..:.|:|...|.||::|:|.||:|:.:.||||||||||.|||||...:
Mouse   424 EGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAY------ 482

  Fly   388 ESDTTESFRGSHF-----------KIEDKSFNALFM-CA--ALCNSAEFKGGQDDIPVFKKDVNG 438
                   ..|:|:           |:.:...|.:.: ||  :.....|.:||   :|   :.| |
Mouse   483 -------IGGTHYRQIPQPDVFPPKVLELIVNGISINCAYTSKIQPPEKEGG---LP---RQV-G 533

  Fly   439 NASEAALLKFTETIFAGIGAFRQKHIKLTEIP---------FNSTEKYQVSVHEFNSSDGYFIVE 494
            |.:|..||.|...:.....|.|      .|:|         |||..|...:|  ....:|.|.:.
Mouse   534 NKTECGLLGFVTDLKQDYQAVR------NEVPEEKLFKVYTFNSVRKSMSTV--IRKPEGGFRMF 590

  Fly   495 MKGAPERILDRCSTIIIQGLSVELTPTLKLEFEEAYLEMGGMGERVLGFADLLLPMSK-----YP 554
            .|||.|.:|.||..|:               .:|..::.....:|.....:::.||:.     ..
Mouse   591 SKGASEIMLRRCDRIL---------------NKEGEIKSFRSKDRDNMVRNVIEPMASEGLRTIC 640

  Fly   555 ISY-EFSADPPNFPLE-----NLRFLGLISLIDPPRAAVPDAVAKCRSAGVRVIMVTGDHPITAK 613
            ::| :|....|::.:|     :|..:.::.:.||.|..||||:|||:.||:.|.|||||:..||:
Mouse   641 LAYRDFDGTEPSWDIEGEILTSLICIAVVGIEDPVRPEVPDAIAKCKRAGITVRMVTGDNVNTAR 705

  Fly   614 AIARSVGIITTPTAEDIAKQRGVTVLDIDSRQATAIVVHGGELREMKAEELDAVIYYHNEIVFAR 678
            |||...||:|  ..:|.        |.::.::..:::  ..|..|::.|:||.:  :....|.||
Mouse   706 AIATKCGILT--PKDDF--------LCLEGKEFNSLI--RNEKGEVEQEKLDKI--WPKLRVLAR 756

  Fly   679 TSPQQKLIIVE------ACQRRGEIVAVTGDGVNDSPALKRADIGVAMGISGSDVSKQAADMILL 737
            :||..|..:|:      |.::| ::|||||||.||.||||:||:|.||||:|:||:|:|:|:||.
Mouse   757 SSPTDKHTLVKGIIDSTAGEQR-QVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILT 820

  Fly   738 DDNFASIVVGIEEGRIIFDNLKKSIAYTLTSNLPEIVPFLFFVIF-------DIPLALGTIAILC 795
            ||||.|||..:..||.::|::.|.:.:.||.|:..::     |.|       |.||.  .:.:|.
Mouse   821 DDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVI-----VAFTGACITQDSPLK--AVQMLW 878

  Fly   796 IDIGTDMLPAISLAYEKAESDIMARMP---RDPFEDRLVNKKLILMAYLQIGVIQTVACFFTFFA 857
            :::..|...:::||.|.....::.|.|   ..|...|.:.|.::..|..|:.::     |...||
Mouse   879 VNLIMDTFASLALATEPPTESLLRRRPYGRNKPLISRTMMKNILGHAVYQLLIV-----FLLVFA 938

  Fly   858 IMAEHGFPPSRLKGIREDWDSKNVEDLEDGYGQEWTYRERKVLEYTAGTGFFVSIVVTQVFDLLI 922
              .:..|          |.||.....|.....|.:|.             .|.:.|:.|:|
Mouse   939 --GDTLF----------DIDSGRKAPLNSPPSQHYTI-------------VFNTFVLMQLF---- 974

  Fly   923 CKTRRNSILQQGMGNHVLNFALVLEFIIAC------LLCYVPVFE---KTLRMYSIKFIWWIYAF 978
                 |.|..:.:......||.|...||.|      ..|.:.:.|   |.....|:....|::..
Mouse   975 -----NEINARKIHGEKNVFAGVYRNIIFCTVVLGTFFCQIMIVELGGKPFSCTSLTMEQWMWCL 1034

  Fly   979 PFGL 982
            ..|:
Mouse  1035 FIGI 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JYalpha	NP_001104092.2	ATPase-IIC_X-K	17..1009	CDD:273445	302/1109 (27%)
		Cation_ATPase_N	29..102	CDD:214842	24/86 (28%)
		E1-E2_ATPase	123..354	CDD:278548	83/312 (27%)
		Cation_ATPase	416..509	CDD:289987	29/101 (29%)
		COG4087	<673..738	CDD:226572	37/70 (53%)
		Cation_ATPase_C	785..994	CDD:279079	42/210 (20%)
Atp2b4	XP_011246340.1	ATPase-IIB_Ca	16..1053	CDD:273668	302/1109 (27%)
		ATP_Ca_trans_C	1090..1169	CDD:372101

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010