Protein Alignment JYalpha and Atp2b3

DIOPT Version :9

• Sequence 1: NP_001104092.2
• Gene: JYalpha / 5740846
• FlyBaseID: FBgn0267363
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: XP_006528144.1
• Gene: Atp2b3 / 320707
• MGIID: 1347353
• Length: 1249
• Species: Mus musculus
• Alignment Length: 1256
• Identity: 326/1256 - (25%)
• Similarity: 502/1256 - (39%)
• Gaps: 406/1256 - (32%)

  Fly    11 KINGKEKKKDIQSFKKDVETDNHKIPVDELLERLKTDPNMGL--SFVEAKLRLEINGPNILTPQP 73
            ::.|.|..:.||....|         |..|..||||.|..||  :..:.:.|.:|.|.|.:.|:.
Mouse    39 ELRGAEALQKIQEAYGD---------VSGLCRRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQ 94

  Fly    74 PTPKWIVFLKTMFGGFAILLWAG-----SFLCFVGYLIQLQTQ-HEPPDDNLYL----------- 121
            |        ||    |..|:|..     ..:..|..::.|... :.||.:....
Mouse    95 P--------KT----FLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGAEDE 147

  Fly   122 ---------GIALTVLVIVTGLFTYFQVHKSSSIMDSFKNLVPQYA--TVIREGEINTVTSDEIV 175
                     |.|:.:.||...|.|.|............::.:.|..  ||||.|::..|....:|
Mouse   148 GEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALV 212

  Fly   176 KGDIVEVKFGDRVPADIRILEAHGLKVDNSSLTGESEPQVRSTEFTHENPLETKNLAFFSTNVLE 240
            .|||.:||:||.:|||..:::.:.||:|.|||||||:...:|.:   ::|     :....|:|:|
Mouse   213 VGDIAQVKYGDLLPADGVLIQGNDLKIDESSLTGESDHVRKSAD---KDP-----MLLSGTHVME 269

  Fly   241 GTCRGVVIATGDSTVMGRIANL--AAG----------------LDDVQS-------PISREIQ-- 278
            |:.|.||.|.|.::..|.|..|  |.|                :|..|:       .::.|:|
Mouse   270 GSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMDSSQTRAKKQDGAVAMEMQPL 334

  Fly   279 -----------------------------------------LFIRFITIFAIILGLSFFAISLTL 302
                                                     |.:..||:..::|   :|.|...:
Mouse   335 KSAEGGEMEEREKKKANVPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVL---YFVIETFV 396

  Fly   303 GYEFIDAVV----------------FLIG--IIVANVPEGLLVTVTVCLTLTAKRMASKNCLVKN 349
                :|..|                |:||  ::|..|||||.:.||:.|..:.|:|...|.||::
Mouse   397 ----VDGRVWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRH 457

  Fly   350 LEAVETLGSTSTICSDKTGTLTQNRMTVAHLW-----YDQIIVESDTTESFRGSHFKIEDKSFNA 409
            |:|.||:|:.:.||||||||||.|||||...:     |.:|...|..|.       ||.|
Mouse   458 LDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTP-------KILD----- 510

  Fly   410 LFMCAALCNSA--------EFKGGQDDIPVFKKDVNGNASEAALLKFTETIFAGIGAFRQKHIKL 466
            |.:.|...|||        |.:|.   :|   :.| ||.:|.|||.|...:.......|:
Mouse   511 LLVHAISINSAYTTKILPPEKEGA---LP---RQV-GNKTECALLGFVLDLKRDFQPVRE----- 563

  Fly   467 TEIP---------FNSTEKYQVSVHEFNSSDGYFIVEMKGAPERILDRCSTII-----IQGLSVE 517
             :||         |||..|...:|  ....||.|.:..|||.|.:|.:|:.|:     ::|
Mouse   564 -QIPEDQLYKVYTFNSVRKSMSTV--IRMPDGGFRLFSKGASEILLKKCTNILNSNGELRG---- 621

  Fly   518 LTPTLKLEFEEAYLE-MGGMGERVLGFADLLLPMSKYPISY-EFSA-DPPNFPLEN-----LRFL 574
            ..|..:.:..:..:| |...|.|.:            .|:| :||| ..|::..||     |..:
Mouse   622 FRPRDRDDMVKKIIEPMACDGLRTI------------CIAYRDFSAIQEPDWDNENEVVGDLTCI 674

  Fly   575 GLISLIDPPRAAVPDAVAKCRSAGVRVIMVTGDHPITAKAIARSVGIITTPTAEDIAKQRGVTVL 639
            .::.:.||.|..||:|:.||:.||:.|.|||||:..||:|||...|||          |.|...|
Mouse   675 AVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGII----------QPGEDFL 729

  Fly   640 DIDSRQATAIVVHGGELREMKAEELDAVIYYHNEIVFARTSPQQKLIIVEAC-------QRRGEI 697
            .::.::....:  ..|..|::.|.||.|  :....|.||:||..|..:|:..       ||  ::
Mouse   730 CLEGKEFNRRI--RNEKGEIEQERLDKV--WPKLRVLARSSPTDKHTLVKGIIDSTTGEQR--QV 788

  Fly   698 VAVTGDGVNDSPALKRADIGVAMGISGSDVSKQAADMILLDDNFASIVVGIEEGRIIFDNLKKSI 762
            |||||||.||.||||:||:|.||||:|:||:|:|:|:||.||||.|||..:..||.::|::.|.:
Mouse   789 VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 853

  Fly   763 AYTLTSNLPEIVPFLFFVIF-------DIPLALGTIAILCIDIGTDMLPAISLAYEKAESDIMAR 820
            .:.||.|:..::     |.|       |.||.  .:.:|.:::..|...:::||.|.....::.|
Mouse   854 QFQLTVNVVAVI-----VAFTGACITQDSPLK--AVQMLWVNLIMDTFASLALATEPPTESLLLR 911

  Fly   821 MP--RD-PFEDRLVNKKLILMAYLQIGVIQTV--------------------------ACFFTFF 856
            .|  || |...|.:.|.::..|..|:.:|.|:                          ...|..|
Mouse   912 KPYGRDKPLISRTMMKNILGHAVYQLTIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTF 976

  Fly   857 AIM---------AEHG------------------------------------------------- 863
            .:|         ..||
Mouse   977 VMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWC 1041

  Fly   864 ----------------FPPSRLKGIRE-----DWDSKNVEDLEDG------------YGQEWTYR 895
                            .|.|:||.::|     ..|....|:|.:|            .||...:|
Mouse  1042 LFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILWFR 1106

  Fly   896 -------ERKVLEYTAGTGFFV------SIVVTQVFDLLICKTRRNSILQQGM-----GNHVLNF 942
                   :.:|:.....:|.|.      |.|::|:.|:.:.|..|:| |.:|:     .:.:.||
Mouse  1107 GLNRIQTQMEVVSTFKRSGSFQGAVRRRSSVLSQLHDIRVVKAFRSS-LYEGLEKPESKSCIHNF 1170

  Fly   943 ALVLEFIIACLLCYVPVFEKT 963
            ....||:|......:|:.:.|
Mouse  1171 MATPEFLINDYTHNIPLIDDT 1191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JYalpha	NP_001104092.2	ATPase-IIC_X-K	17..1009	CDD:273445	324/1250 (26%)
		Cation_ATPase_N	29..102	CDD:214842	20/79 (25%)
		E1-E2_ATPase	123..354	CDD:278548	81/318 (25%)
		Cation_ATPase	416..509	CDD:289987	31/109 (28%)
		COG4087	<673..738	CDD:226572	37/71 (52%)
		Cation_ATPase_C	785..994	CDD:279079	54/317 (17%)
Atp2b3	XP_006528144.1	ATPase-IIB_Ca	19..1061	CDD:273668	296/1123 (26%)
		ATP_Ca_trans_C	1100..1175	CDD:372101	17/75 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010