Protein Alignment JYalpha and catp-6

DIOPT Version :9

• Sequence 1: NP_001104092.2
• Gene: JYalpha / 5740846
• FlyBaseID: FBgn0267363
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: NP_001255430.2
• Gene: catp-6 / 177822
• WormBaseID: WBGene00012341
• Length: 1267
• Species: Caenorhabditis elegans
• Alignment Length: 1183
• Identity: 258/1183 - (21%)
• Similarity: 427/1183 - (36%)
• Gaps: 337/1183 - (28%)

  Fly    12 INGKEKKKDIQS----FKKDVETDNHKIPVDELLERLKTDPNMGLSFVEAKLRLEINGPNILTPQ 72
            :|..|...:|..    :|...|..| :||...||  ..::.|.||:..|...|||..|.|.:..|
 Worm   125 LNSDESVDEISDNDNCWKTSFEIAN-RIPCRSLL--AVSESNFGLTLSEISRRLEFYGRNEIVVQ 186

  Fly    73 --PPTPKWIVFLKTM--------FGGFAILLWAGSFLCFVGYLIQLQTQHEPPDDNLYLG-IALT 126
              |     |::|..|        |..|::.:|......:...||.:          |.|| |.:.
 Worm   187 LRP-----ILYLLVMEVITPFYVFQIFSVTVWYNDEYAYYASLIVI----------LSLGSIVMD 236

  Fly   127 VLVIVT-GLFTYFQVHKSSSIMDSFKNLVPQYATVIREGEINTVTSDEIVKGDIVEVKFGDRVPA 190
            |..|.| .:.....||.:.|:            .|||||...|:.||::|.|||:
 Worm   237 VYQIRTQEIRLRSMVHSTESV------------EVIREGTEMTIGSDQLVPGDIL---------- 279

  Fly   191 DIRILEAHG-------------LKVDNSSLTGESEP--QVRSTEFTHENPL----ETKNLAFFST 236
               ::..||             :.|:.|.|||||.|  :|..|:.|:::..    .:||:.|..|
 Worm   280 ---LIPPHGCLMQCDSVLMNGTVIVNESVLTGESVPITKVALTDETNDSVFNIEKNSKNVLFCGT 341

  Fly   237 NVLE------GTCRGVVIATGDSTVMGRIANLAAGLDDVQSPISREIQLFIRFITIFAIILGLSF 295
            .||:      ...:.:|:.|..||:.|::.........|....::::   .:||...|.|.|..|
 Worm   342 QVLQTRFYRGKKVKAIVLRTAYSTLKGQLVRSIMYPKPVDFRFTKDL---FKFILFLACISGCGF 403

  Fly   296 ---FAISLTLGYEFIDAVVFLIGIIVANVPEGLLVTVTVCLTLTAKRMASKNCLVKNLEAVETLG 357
               ..:.:..|......:|..:.||...||..|...::|.:.....|:..|.....:...:.|.|
 Worm   404 IYTIIVMIMRGNTLRRIIVRSLDIITITVPPALPAAMSVGIINAQLRLKKKEIFCISPSTINTCG 468

  Fly   358 STSTICSDKTGTLTQNR---------MTVAHLWYDQIIVESDTTESFRGSHFKIEDKS---FNA- 409
            :.:.:|.|||||||::.         |:..:....::.:|......|.|...::..::   |:.
 Worm   469 AINVVCFDKTGTLTEDGLDFHVVRPVMSAVNQEIQKVKLEKSNRTEFMGEMTELTSRNGLPFDGD 533

  Fly   410 LFMCAALCNS-----AEFKGGQDDIPVFKK-------DVNGNASE---------AALLKFTETIF 453
            |....|.|:|     ....|...|:.:|:|       .:.|:..|         .:::|.|:...
 Worm   534 LVKAIATCHSLTRINGVLHGDPLDLILFQKTGWTMEEGIEGDIEEETQRFDNVQPSIIKPTDDKS 598

  Fly   454 AGIGAFRQKHIKLTEIPFNSTEKYQVSVHEFNSSD---GYFIVEMKGAPERILDRCSTIIIQGLS 515
            |.....||       ..|:|:.: ::||..|:..:   ...::..||:||.||..|....:.
 Worm   599 AEYSVIRQ-------FTFSSSLQ-RMSVIVFDPREDRPDNMMLYSKGSPEMILSLCDPNTVP--- 652

  Fly   516 VELTPTLKLEFEEAYLEMGGMGERVLGFADLLLPMSKYPISYEFS------ADPPNFPLENLRFL 574
                       |:..|::....:.  ||.  |:.:::.|:...|:      .|.....||   .|
 Worm   653 -----------EDYLLQVNSYAQH--GFR--LIAVARRPLDLNFNKASKVKRDAVECDLE---ML 699

  Fly   575 GLISLIDPPRAAVPDAVAKCRSAGVRVIMVTGDHPITAKAIARSVGIIT---------------- 623
            |||.:.:..:......:.:...|.:|.:|||||:.:|..::||..|||.
 Worm   700 GLIVMENRVKPVTLGVINQLNRANIRTVMVTGDNLLTGLSVARECGIIRPSKRAFLVEHVPGELD 764

  Fly   624 --------------------------------------------TPTAEDIAKQRGVTVLDID-- 642
                                                        :||..::.....||...:.
 Worm   765 EYGRTKIFVKQSVSSSDEVIEDDASVSISMCSSTWKGSSEGDGFSPTNTEVETPNPVTADSLGHL 829

  Fly   643 ---------SRQATAIVVHGGELREMKAEELDAVIYYHNEIVFARTSPQQKLIIVEACQRRGEIV 698
                     |....|::||  |..|: .::|.:|.     .||||.:|.||..:||..|:....|
 Worm   830 IASSYHLAISGPTFAVIVH--EYPEL-VDQLCSVC-----DVFARMAPDQKQSLVEQLQQIDYTV 886

  Fly   699 AVTGDGVNDSPALKRADIGVAMGISGSDVSKQAADMILLDDNFASIVVGIEEGRII----FDNLK 759
            |:.|||.||..|||.|..|:::..:.:.:   ||.......:...:...|.|||..    |...|
 Worm   887 AMCGDGANDCAALKAAHAGISLSDAEASI---AAPFTSKVPDIRCVPTVISEGRAALVTSFGIFK 948

  Fly   760 KSIAYTLT-----------SNLPEIVPFLFFVIFDIPLALGTIAILCIDIGTDMLPAISLAYEKA 813
            ....|:||           ||:.....|::..:|       .|.:..:..|.  .||.   |..|
 Worm   949 YMAGYSLTQFVTVMHLYWISNILTDGQFMYIDMF-------LITMFALLFGN--TPAF---YRLA 1001

  Fly   814 ESDIMARMPRDPFEDRLVNKKLILMAYLQIGVIQTVACFFTFFAIMAEHGFPPSRLKGIREDWDS 878
            .:....|:........:|.:.:|      |||:|    |..||:...:..|.|         :..
 Worm  1002 HTPPPTRLLSIASMTSVVGQLII------IGVVQ----FIVFFSTSQQPWFTP---------YQP 1047

  Fly   879 KNVEDLEDGYGQEWTYRERKVLEYTAGTGFFVSIVVTQVFDLLICKTRRNSILQQG---MGNHVL 940
            ...:::||....:             ||..|    ...:|..:|...    :..:|   .||...
 Worm  1048 PVDDEVEDKRSMQ-------------GTALF----CVSMFQYIILAL----VYSKGPPFRGNLWS 1091

  Fly   941 NFALVLEFIIACLLC-YVPVFE-----KTL---RMYSIKFIWWIY-------AFPFGLLIFFFDE 989
            |..:....|.|.||| ::.::.     |||   .:.|:.|..:|.       |..:|....|.|
 Worm  1092 NKPMCALTIFATLLCLFIVIWPTELVLKTLGNVELPSLTFRIFIVIVGAVNAAVSYGFETLFVD- 1155

  Fly   990 SRRFLIRRNPGGW 1002
              .||:    |.|
 Worm  1156 --FFLL----GYW 1162

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JYalpha	NP_001104092.2	ATPase-IIC_X-K	17..1009	CDD:273445	256/1178 (22%)
		Cation_ATPase_N	29..102	CDD:214842	23/82 (28%)
		E1-E2_ATPase	123..354	CDD:278548	60/259 (23%)
		Cation_ATPase	416..509	CDD:289987	25/116 (22%)
		COG4087	<673..738	CDD:226572	24/64 (38%)
		Cation_ATPase_C	785..994	CDD:279079	44/227 (19%)
catp-6	NP_001255430.2	P-ATPase-V	18..1137	CDD:273738	250/1149 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910