Protein Alignment JYalpha and sca-1

DIOPT Version :9

• Sequence 1: NP_001104092.2
• Gene: JYalpha / 5740846
• FlyBaseID: FBgn0267363
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: NP_499386.1
• Gene: sca-1 / 176512
• WormBaseID: WBGene00004736
• Length: 1059
• Species: Caenorhabditis elegans
• Alignment Length: 1050
• Identity: 297/1050 - (28%)
• Similarity: 502/1050 - (47%)
• Gaps: 146/1050 - (13%)

  Fly    31 DNHKIPVDELLERLKTDPNMGLSFVEAKLRLEINGPNILTPQPPTPKWIVFLKTMFGGF--AILL 93
            |.|....:|:.:...|.|. ||:..:.:......|.|.:..:.....|.:.|: .|...  .|||
 Worm     3 DAHAKDANEVCKFFGTGPE-GLTPQQVETLRNKYGENEMPAEEGKSLWELILE-QFDDLLVKILL 65

  Fly    94 WAGSFLCFVGYLIQLQTQHEPPDDNLYLGI---ALTVLVIVTGLFTYFQVHKSSSIMDSFKNLVP 155
            .|    ..:.:::.|..:||...:.:...:   .:.:::|.......:|...:.|.:::.|...|
 Worm    66 LA----AIISFVLALFEEHEDQTEAVTAFVEPFVILLILIANATVGVWQERNAESAIEALKEYEP 126

  Fly   156 QYATVIREGE--INTVTSDEIVKGDIVEVKFGDRVPADIRILEAHG--LKVDNSSLTGESEPQVR 216
            :.|.|||.|.  |..|.:.|:|.||:|||..||::|||:|:::.:.  :::|.|.|||||...::
 Worm   127 EMAKVIRSGHHGIQMVRAKELVPGDLVEVSVGDKIPADLRLVKIYSTTIRIDQSILTGESVSVIK 191

  Fly   217 STEFTHENPL---ETKNLAFFSTNVLEGTCRGVVIATGDSTVMGRIANLAAGLDDVQSPISREIQ 278
            .|:...:...   :.||..|..|||..|..||:|..||.:|.:|:|....|..::.::|:.:::.
 Worm   192 HTDSVPDPRAVNQDKKNCLFSGTNVASGKARGIVFGTGLTTEIGKIRTEMAETENEKTPLQQKLD 256

  Fly   279 LFIRFITIFAIILGLSFFAISL------TLGYEFIDAVVF----LIGIIVANVPEGLLVTVTVCL 333
            .|...::....::.::.:||::      ..|..::...::    .:.:.||.:||||...:|.||
 Worm   257 EFGEQLSKVISVICVAVWAINIGHFNDPAHGGSWVKGAIYYFKIAVALAVAAIPEGLPAVITTCL 321

  Fly   334 TLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLW-----------YDQIIV 387
            .|..:|||.||.:|::|.:|||||.||.||||||||||.|:|:|:.::           :.:..:
 Worm   322 ALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSKMFIAGQASGDNINFTEFAI 386

  Fly   388 ESDTTE-----SFRGSHFKI---EDKSFNALFMCAALCNSAEFKGGQDDIPVFKK--DVNGNASE 442
            ...|.|     |..|.....   |.:|...|.|..|:||.:..     |....||  :..|.|:|
 Worm   387 SGSTYEPVGKVSTNGREINPAAGEFESLTELAMICAMCNDSSV-----DYNETKKIYEKVGEATE 446

  Fly   443 AALLKFTE------TIFAGIG----------AFRQKHIKLTEIPFNSTEKYQVSVHEFNSSDG-- 489
            .||:...|      |..||:.          ..:||..|...:.| |.::..:|.:.|.:|.|
 Worm   447 TALIVLAEKMNVFGTSKAGLSPKELGGVCNRVIQQKWKKEFTLEF-SRDRKSMSAYCFPASGGSG 510

  Fly   490 --YFIVEMKGAPERILDRCSTIIIQGLSVELTPTLKLEFEEAYLEMGGMGE--RVLGFADLLLPM 550
              .|:   |||||.:|.||:.:.:.|..|.||..:..:..:..::.|...:  |.|....:..|:
 Worm   511 AKMFV---KGAPEGVLGRCTHVRVNGQKVPLTSAMTQKIVDQCVQYGTGRDTLRCLALGTIDTPV 572

  Fly   551 SKYPISYEFSADPPNFPLENLRFLGLISLIDPPRAAVPDAVAKCRSAGVRVIMVTGDHPITAKAI 615
            |...::.|.|.....:. :::.|:|::.::||||..|.|::..|..||:||||:|||:..||:||
 Worm   573 SVSNMNLEDSTQFVKYE-QDITFVGVVGMLDPPRTEVSDSIKACNHAGIRVIMITGDNKNTAEAI 636

  Fly   616 ARSVGIITTPTAEDIAKQRGVTVLDIDSRQATAIVVHGGELREMKAEELDAVIYYHNEIVFARTS 680
            .|.:|:..                  ::...|.....|.|..::..|:.....  ....:|||..
 Worm   637 GRRIGLFG------------------ENEDTTGKAYTGREFDDLPPEQQSEAC--RRAKLFARVE 681

  Fly   681 PQQKLIIVEACQRRGEIVAVTGDGVNDSPALKRADIGVAMGISGSDVSKQAADMILLDDNFASIV 745
            |..|..||:..|.:|||.|:|||||||:||||:|:||::|| ||:.|:|.|::|:|.||||||||
 Worm   682 PSHKSKIVDILQSQGEITAMTGDGVNDAPALKKAEIGISMG-SGTAVAKSASEMVLADDNFASIV 745

  Fly   746 VGIEEGRIIFDNLKKSIAYTLTSNLPEIVPFLFFVIFDIPLALGTIAILCIDIGTDMLPAISLAY 810
            ..:||||.|::|:|:.|.|.::||:.|:|.........||.||..:.:|.:::.||.|||.:|.:
 Worm   746 SAVEEGRAIYNNMKQFIRYLISSNVGEVVSIFMVAALGIPEALIPVQLLWVNLVTDGLPATALGF 810

  Fly   811 EKAESDIMARMPRDPFEDRLVNKKLILMAYLQIGV---IQTVACFFTFFAIMAE----------H 862
            ...:.|||.|.||.. .|.|::..| ...||.:|.   :.||.....:|.:..|          |
 Worm   811 NPPDLDIMDRHPRSA-NDGLISGWL-FFRYLAVGTYVGVATVGASMWWFLLYEEGPQITYYQLTH 873

  Fly   863 GFPPSRLKGIREDWDSKNVEDLEDGYGQEWTYRERKVLEYTAGTGFFVSIVVT-QVFDLLICKTR 926
                    .:|.:.:..|..||:..           |.|........:|::|| ::.:.:...:.
 Worm   874 --------WMRCEIEPDNFADLDCA-----------VFEDNHPNAMALSVLVTIEMLNAINSLSE 919

  Fly   927 RNSILQQGMGNHV-----LNFALVLEFIIACLLCYVPVFEKTLRMYSIKFIWWIYAFPFGLLIFF 986
            ..|:|......::     ::.::.|.|:|    .||.:.....::..:.::.||......|.:..
 Worm   920 NQSLLVMPPWKNIWLMAAISLSMSLHFVI----LYVDIMATIFQITPLNWVEWIAVLKISLPVLL 980

  Fly   987 FDESRRFLIR 996
            .||..:|:.|
 Worm   981 LDEILKFIAR 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JYalpha	NP_001104092.2	ATPase-IIC_X-K	17..1009	CDD:273445	296/1049 (28%)
		Cation_ATPase_N	29..102	CDD:214842	16/72 (22%)
		E1-E2_ATPase	123..354	CDD:278548	71/250 (28%)
		Cation_ATPase	416..509	CDD:289987	32/114 (28%)
		COG4087	<673..738	CDD:226572	35/64 (55%)
		Cation_ATPase_C	785..994	CDD:279079	48/227 (21%)
sca-1	NP_499386.1	Cation_ATPase_N	4..71	CDD:279080	15/72 (21%)
		ATPase-IIA1_Ca	52..990	CDD:273452	286/998 (29%)
		E1-E2_ATPase	95..342	CDD:278548	71/246 (29%)
		Cation_ATPase	423..529	CDD:289987	32/114 (28%)
		HAD	<607..713	CDD:289480	43/125 (34%)
		Cation_ATPase_C	785..988	CDD:279079	48/227 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920