Protein Alignment Shawl and kcna1a

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: XP_005163101.1
• Gene: kcna1a / 795942
• ZFINID: ZDB-GENE-110408-15
• Length: 492
• Species: Danio rerio
• Alignment Length: 551
• Identity: 164/551 - (29%)
• Similarity: 252/551 - (45%)
• Gaps: 151/551 - (27%)

  Fly     6 RIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYRT-GKL 69
            |:::|::|:|:||...||.:.|.|.|....:.:..:||:.|||||||:...|..||.||:: |:|
Zfish    35 RVVINIAGLRFETQLKTLAQFPETLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRL 99

  Fly    70 HYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEEQIARLF 134
            ..|.:|...:|.||::|:.|....:|.        .|:.:..:.       |.|:|..|
Zfish   100 RRPANVPLDMFSEEIKFYELGVEAMEK--------FREDEGFIR-------EEERPLPE------ 143

  Fly   135 GFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPGFRVDLP 199
                          :..:.:||.:|:.|.||..|:.:|.:||..|.:|::.|||:|.|..:.|
Zfish   144 --------------KEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKED-- 192

  Fly   200 SGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGNFTASGQA 264
                                                 |.|.|    ::...|:|
Zfish   193 -------------------------------------PEGRI----KIIGNTTY----------- 205

  Fly   265 TPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVELVCNVWFF 329
                                     :.:..||.                 :.||.:|.:|.:||.
Zfish   206 -------------------------YYKPSILA-----------------DPFFIIETLCIIWFS 228

  Fly   330 IEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY----------TDVMQRMGEYT---GLLEAFSI 381
            .|:|:|....|:...|.|:.:|.||..|.:.::          .|..:..||..   .:|....:
Zfish   229 FELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITLGTELAEEQDGKEGKGEQATSLAILRVIRL 293

  Fly   382 VRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKSI 446
            ||:.|:|||:|||.||:||..|.|||.:||.||:|||.:|::.|:|..|:||  .:..::.|.||
Zfish   294 VRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE--AEEKESYFSSI 356

  Fly   447 PLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQARSKL 511
            |...|||:|:||||||||:.|.|..|..||:|||:|||||||||||||||||:.|| |.:...
Zfish   357 PDAFWWAVVSMTTVGYGDMVPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEG-- 418

  Fly   512 PKKRRRVLPVEQPRRKREPTAPHRGRTNAIK 542
             :::.::|.|..|....:..:..|..:...|
Zfish   419 -EEQAQLLNVSNPNIASDSNSSRRSSSTVSK 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	34/92 (37%)
		BTB_2	7..97	CDD:280393	34/90 (38%)
		Ion_trans	307..506	CDD:278921	94/211 (45%)
		Ion_trans_2	<449..499	CDD:285168	36/49 (73%)
kcna1a	XP_005163101.1	BTB	36..130	CDD:197585	35/101 (35%)
		BTB_2	36..127	CDD:280393	34/98 (35%)
		Ion_trans	205..415	CDD:278921	97/265 (37%)
		Ion_trans_2	330..406	CDD:285168	44/77 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810