Protein Alignment Shawl and kcna6a

DIOPT Version :10

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_001124098.1
• Gene: kcna6a / 795490
• ZFINID: ZDB-GENE-080722-21
• Length: 475
• Species: Danio rerio
• Alignment Length: 546
• Identity: 171/546 - (31%)
• Similarity: 249/546 - (45%)
• Gaps: 163/546 - (29%)

  Fly     7 IILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYRT-GKLH 70
            :.:|:||:|:||...||.:.|.|.|....:.:..:||:.||:||||:...|..||.||:: |:|.
Zfish    33 VTINISGLRFETQLKTLARYPNTLLGDPIKRMRFFDPLRNEFFFDRNRPSFDAILYYYQSGGRLR 97

  Fly    71 YPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEEQIARLFG 135
            .|.:|...:|.:|::|:.:..:.:           :..|....:|.    |:|:|
Zfish    98 RPINVPVDMFLDEIKFYEIGDDVI-----------KHFQEDEGLLK----EDERP---------- 137

  Fly   136 FEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPGFRVDLPS 200
                |.:.|      .|.:||.:|:.|.||..|:|:|.:||..|.:|:|.||::|.|.||.|  .
Zfish   138 ----LPSNE------FKRQIWLLFEHPDSSGAARIIAIVSVMVILISIIIFCIETLPEFRED--D 190

  Fly   201 GAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGNFTASGQAT 265
            ...|.|.|                                               .|.|.|.|.
Zfish   191 RVFDNHLP-----------------------------------------------ANSTTSVQR- 207

  Fly   266 PIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVELVCNVWFFI 330
                                                     :..|..|   ||.:|.:|.|||..
Zfish   208 -----------------------------------------LSAYTDP---FFLLETICIVWFCF 228

  Fly   331 EVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDVMQRMGEY---------TGLLEAFSIVRIMR 386
            |:.||.:..|:...|.|..:|.||..|.:.::..:...:||.         ..:|....:||:.|
Zfish   229 ELFIRFLACPSKPTFFKDIMNTIDIVAIMPYFITLSLELGEVQSNQQQTTSLAILRVIRLVRVFR 293

  Fly   387 LFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKSIPLGLW 451
            :|||:|||.||:||..|.:||.:||.||:|||::||:.|:|..|:||  .|:|:..|.|||...|
Zfish   294 IFKLSRHSKGLQILGQTLRASMRELGLLIFFLIIGIILFSSAVYFAE--ADDPETSFTSIPDAFW 356

  Fly   452 WAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFY--SHTQA------- 507
            ||:|:||||||||:.|.|..|..||::||:|||||||||||||||||:.||  .|.:|
Zfish   357 WAVVSMTTVGYGDMYPVTIGGKIVGSMCAIAGVLTIALPVPVIVSNFNYFYHREHNEADQVEYTH 421

  Fly   508 ----RSKLPKKRRRVLPVEQPRRKRE 529
                ||         ||::..|.|.:
Zfish   422 VTCGRS---------LPMQCDRNKSD 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB_Shaw-like	4..115	CDD:349723	32/108 (30%)
		Ion_trans	307..506	CDD:459842	97/209 (46%)
kcna6a	NP_001124098.1	BTB_POZ	31..157	CDD:453885	43/158 (27%)
		Ion_trans	203..411	CDD:459842	98/254 (39%)