Protein Alignment Shawl and Kcnv1

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_080476.2
• Gene: Kcnv1 / 67498
• MGIID: 1914748
• Length: 503
• Species: Mus musculus
• Alignment Length: 539
• Identity: 137/539 - (25%)
• Similarity: 216/539 - (40%)
• Gaps: 165/539 - (30%)

  Fly     9 LNVSGIRYETYKATLKKIPATRLSRLTEALANY-------------------DPVLNEYFFDRHP 54
            :||.|.|:...:..|...|.|||.:|...:|:|                   :||.|||||||..
Mouse    46 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSS 110

  Fly    55 GVFTQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLD 119
            ..|..:|:|||||:||....:|...|.:|:::||:|...::.||...|...::...||..  |.|
Mouse   111 QAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDF--KKD 173

  Fly   120 IENEKPTEEQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVI 184
            .::::...|.       |:..|.|.  | ..::.|:|.:.::|.|||.|:|...:|:.|:.||::
Mouse   174 TDDQESQHES-------EQDFSKGP--C-PTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIV 228

  Fly   185 SFCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTN 249
            :..|.:
Mouse   229 NMALMS----------------------------------------------------------- 234

  Fly   250 YTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPH 314
                                                                .:..|:..
Mouse   235 ----------------------------------------------------AELSWLNL----- 242

  Fly   315 EAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY-------------TDVM 366
            :....:|.||..||..|.::|.:...:...|::...||||..|.|.||             |..:
Mouse   243 QLLEILEYVCISWFTGEFVLRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQEL 307

  Fly   367 QRMGEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYY 431
            :.:|.   |::...::|.:|:.||.|||.|||.|..|.....:|:.||:.||.:||..|:::.|:
Mouse   308 ENVGR---LVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYF 369

  Fly   432 AEKLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVS 496
            ||  |..||..|.|:|...|||..:||||||||:.|.|..|..|..:|.|:|:|.:|||:.:|..
Mouse   370 AE--QSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIIND 432

  Fly   497 NFSMFYSHTQARSKLPKKR 515
            .||..|...:.:....::|
Mouse   433 RFSACYFTLKLKEAAVRQR 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	37/108 (34%)
		BTB_2	7..97	CDD:280393	36/106 (34%)
		Ion_trans	307..506	CDD:278921	74/211 (35%)
		Ion_trans_2	<449..499	CDD:285168	23/49 (47%)
Kcnv1	NP_080476.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		BTB_POZ	44..163	CDD:365784	39/116 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..192		6/29 (21%)
		Ion_trans	212..438	CDD:366146	81/346 (23%)
		Selectivity filter. /evidence=ECO:0000250	395..400		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910