Protein Alignment Shawl and Kcng4

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_080010.2
• Gene: Kcng4 / 66733
• MGIID: 1913983
• Length: 506
• Species: Mus musculus
• Alignment Length: 586
• Identity: 149/586 - (25%)
• Similarity: 224/586 - (38%)
• Gaps: 169/586 - (28%)

  Fly     7 IILNVSGIRYETYKATLKKIPATRLSRL---------TEALANYDPVLNEYFFDRHPGVFTQILN 62
            |::||.|.||....:||...|.:|||||         |:...:||....|:||||:|..|..|::
Mouse    60 ILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSHEEITQLCDDYDEDSQEFFFDRNPSAFGVIVS 124

  Fly    63 YYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTE 127
            :...|||....::|...|.|||.:||::...:|.||            ...:|.||:...|...|
Mouse   125 FLAAGKLVLLREMCALSFREELSYWGIEETNLERCC------------LRKLLKKLEEAAELRRE 177

  Fly   128 EQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHP 192
            |...|....:...|..:.:.|.|...::..|.::|.|....|:.|.:||.|:..:.:|.|:.|.|
Mouse   178 EAAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMP 242

  Fly   193 GFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGN 257
            .||.:
Mouse   243 DFRAE------------------------------------------------------------ 247

  Fly   258 FTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVEL 322
             ...|:.|                                    ||..:|          |.||.
Mouse   248 -EGKGECT------------------------------------RKCYYI----------FVVES 265

  Fly   323 VCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDV------------------MQRM 369
            :|..||.:|..:|.:.:||..||.:.|:|:||..|...:|..:                  ::::
Mouse   266 ICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDESPEAGERPSSSSYLEKV 330

  Fly   370 GEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEK 434
            |....:|.|..|:.:||   |.|||.||:.|..|.:..|:|..||:.||.:.:..|:.|.|.||.
Mouse   331 GLVLRVLRALRILYVMR---LARHSLGLQTLGLTVRRCAREFGLLMLFLAVAVTLFSPLVYVAEN 392

  Fly   435 LQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFS 499
             :.....:|.|||...||||::||||||||:.|::.||..|.....|:|:|.:|.|...|...||
Mouse   393 -ESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFS 456

  Fly   500 MFYSHTQARSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQTPPTGPGLVAGGVVPVGAGGP 564
            ..|...:...:..:.|.|.|.......:||..:.                   ...:||.|...|
Mouse   457 HSYLELKREQEQVQARLRRLQNTNSASERELLSD-------------------VDDLVPEGLTSP 502

  Fly   565 G 565
            |
Mouse   503 G 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	37/100 (37%)
		BTB_2	7..97	CDD:280393	36/98 (37%)
		Ion_trans	307..506	CDD:278921	73/216 (34%)
		Ion_trans_2	<449..499	CDD:285168	22/49 (45%)
Kcng4	NP_080010.2	BTB_POZ	58..167	CDD:365784	39/118 (33%)
		Ion_trans	219..463	CDD:366146	88/354 (25%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	416..421		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900