Protein Alignment Shawl and Kcnk10

DIOPT Version :10

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_075584.1
• Gene: Kcnk10 / 65272
• RGDID: 619732
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 138
• Identity: 31/138 - (22%)
• Similarity: 56/138 - (40%)
• Gaps: 41/138 - (29%)

  Fly   369 MGEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAE 433
            :|:..|.:...||.|:.::|:..:.|.....:|.|           :.|::.|.:.|.::
  Rat   202 IGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVIST-----------ILFILAGCIVFVTI----- 250

  Fly   434 KLQDNPDNQFKSIP-----LGLWWAIVTMTTVGYGDVA--------------PKTYPGMFVGALC 479
                 |...||.|.     ..:::.:||:||||:||..              |..:..:.|| |.
  Rat   251 -----PAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVG-LA 309

  Fly   480 ALAGVLTI 487
            ..|.||::
  Rat   310 YFAAVLSM 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB_Shaw-like	4..115	CDD:349723
		Ion_trans	307..506	CDD:459842	31/138 (22%)
Kcnk10	NP_075584.1	Ion_trans_2	<150..206	CDD:462301	1/3 (33%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	167..172
		Ion_trans_2	244..323	CDD:462301	20/85 (24%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	276..281		3/4 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	412..444