Protein Alignment Shawl and kcnv2b

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_001122212.1
• Gene: kcnv2b / 567780
• ZFINID: ZDB-GENE-060526-28
• Length: 527
• Species: Danio rerio
• Alignment Length: 551
• Identity: 140/551 - (25%)
• Similarity: 222/551 - (40%)
• Gaps: 167/551 - (30%)

  Fly     9 LNVSGIRYE-TYKATLKKIPATRLSRLT---------EALANYDPVLNEYFFDRHPGVFTQILNY 63
            |||.|..|. |||.. .:.|.|||.||.         :...:|....|||||||.|.||..|.|:
Zfish    84 LNVGGKSYRITYKMA-ARYPQTRLGRLAMSTDLNMKMDLCDDYVVKDNEYFFDRDPDVFNSIFNF 147

  Fly    64 YRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEE 128
            ||||.|....::|...|.||:.:||:.....:.||    .|..:.:|. .:.::|.::.|...|.
Zfish   148 YRTGVLWIKDELCPRNFLEEISYWGVRIKYSQRCC----RILLEEKND-ELCEQLKVQKELEREL 207

  Fly   129 QIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPG 193
            :|..   .|||..:..|...:|   .:|...::|.||..||::|..|..|:.:|:::..|.|
Zfish   208 EIEE---NEEAFDDMILGESRR---SLWDFMEKPFSSIPAKLMAVTSSMFVLISLVTMTLST--- 263

  Fly   194 FRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGNF 258
                                                                             
Zfish   264 ----------------------------------------------------------------- 263

  Fly   259 TASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVELV 323
                                            :||.   .|       ||:.|:.:..|  ||.:
Zfish   264 --------------------------------VEEM---EN-------IESEGKNYGEF--VENL 284

  Fly   324 CNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATL---------SFYT----------DVMQRM 369
            |..:|.||.::|:|.:|::.:|.||.:|.:|..|.|         :|.|          :.:.::
Zfish   285 CITFFTIEYLLRVISTPDICRFFKSMLNAVDLMAILPQILQFMLENFETFGSRNQSADMETVGQV 349

  Fly   370 GEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEK 434
            |:...:|....::||.|:.||.|||.|||....|.|...:::..|..|:.:||..|:::.|..|
Zfish   350 GKVGQVLRIMRLLRIFRVLKLARHSTGLRAFGFTLKQCYQQVGCLFLFIAMGIFTFSAMVYSVE- 413

  Fly   435 LQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFS 499
             .|.|...|.|||...|||.|:::||||||:.|:|..|......|...|::...||:.::.:.||
Zfish   414 -YDVPKTNFTSIPHSWWWASVSISTVGYGDMYPETLLGRIFAFGCISFGIILNGLPISILFNKFS 477

  Fly   500 MFY---------SHTQARSK---LPKKRRRV 518
            .:|         ||.:.|..   :|:.::::
Zfish   478 DYYAKLKSHECPSHMKNRGNVNFIPRAKKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	39/99 (39%)
		BTB_2	7..97	CDD:280393	38/97 (39%)
		Ion_trans	307..506	CDD:278921	72/226 (32%)
		Ion_trans_2	<449..499	CDD:285168	17/49 (35%)
kcnv2b	NP_001122212.1	BTB	82..173	CDD:295341	37/89 (42%)
		BTB	84..187	CDD:197585	41/107 (38%)
		Ion_trans	279..484	CDD:278921	67/208 (32%)
		Ion_trans_2	409..478	CDD:285168	26/70 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910