Protein Alignment Shawl and kcnv2a

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: XP_695650.4
• Gene: kcnv2a / 567267
• ZFINID: ZDB-GENE-091117-27
• Length: 518
• Species: Danio rerio
• Alignment Length: 530
• Identity: 135/530 - (25%)
• Similarity: 212/530 - (40%)
• Gaps: 155/530 - (29%)

  Fly     9 LNVSGIRYETYKATLKKIPATRLSRLT---------EALANYDPVLNEYFFDRHPGVFTQILNYY 64
            :||.|..|:.......|.|.||:.||.         :...:|....||:||||.|.||..|.|:|
Zfish    86 INVGGKVYQISYRVAAKYPKTRIGRLATYTDHNRKLDLCDDYTVHNNEFFFDRDPDVFHNIFNFY 150

  Fly    65 RTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQN-TLAILDKLDIENEKPTEE 128
            |||.|....::|...|.||:.:||:.......||..::...:|..| .|.:..:|:.|.|....|
Zfish   151 RTGVLWIKDELCPRNFLEEINYWGVRIKNTHRCCRISFEERQDELNEQLKVQRELEAEVETEEHE 215

  Fly   129 QIAR--LFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTH 191
            .:.:  .||....|              ||.|.::|.||..|||:|..|.||:.||:::..|.|
Zfish   216 DLFQDMAFGHTRFL--------------IWNMMEKPFSSIIAKIMAVASSFFVLVSLVAMTLNT- 265

  Fly   192 PGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSG 256
                                            .:..||
Zfish   266 --------------------------------VEEMQY--------------------------- 271

  Fly   257 NFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVE 321
             .|.:||                  ::|                       :||.:      |||
Zfish   272 -ITTNGQ------------------LSG-----------------------KTYCE------YVE 288

  Fly   322 LVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY-------------------TDVMQ 367
            ..|..:|.:|.::||:.:|:|.:|.:|.:|.:|..|.|..|                   .:.:.
Zfish   289 TFCIAFFTMEYLLRLVSTPDLTRFGRSVLNAVDLIAILPLYLQMVLESFESHDYWKHGSDIETVG 353

  Fly   368 RMGEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYA 432
            |:|:...:|....::||.|:.||.|||.|||....|.:...:::..|..|:.:||:.|:::.|..
Zfish   354 RVGKLGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLFLFIAMGILTFSAMVYTV 418

  Fly   433 EKLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSN 497
            |  .|.....|.|||...|||.|:::||||||:.|:|:.|......|...|::...:|:.::.:.
Zfish   419 E--HDVHKTNFTSIPHAWWWAAVSISTVGYGDMFPETHLGRIFAFACISFGIILNGMPISILFNK 481

  Fly   498 FSMFYSHTQA 507
            ||.:||..:|
Zfish   482 FSDYYSKLKA 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	34/98 (35%)
		BTB_2	7..97	CDD:280393	33/96 (34%)
		Ion_trans	307..506	CDD:278921	66/217 (30%)
		Ion_trans_2	<449..499	CDD:285168	16/49 (33%)
kcnv2a	XP_695650.4	BTB	84..175	CDD:295341	32/88 (36%)
		BTB	86..175	CDD:197585	32/88 (36%)
		Ion_trans	285..490	CDD:278921	64/212 (30%)
		Ion_trans_2	403..484	CDD:285168	28/82 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910