Protein Alignment Shawl and kcng2

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: XP_690900.2
• Gene: kcng2 / 562421
• ZFINID: ZDB-GENE-100701-1
• Length: 546
• Species: Danio rerio
• Alignment Length: 608
• Identity: 156/608 - (25%)
• Similarity: 247/608 - (40%)
• Gaps: 172/608 - (28%)

  Fly     8 ILNVSGIRYETYKATLKKIPATRLSRL---------TEALANYDPVLNEYFFDRHPGVFTQILNY 63
            |:||.||||....:||::.|.|||.||         .:...:||...||:||||.|..|..|:.:
Zfish    73 IINVGGIRYRIPWSTLEEFPLTRLGRLHNCNNAEEILDLCDDYDARCNEFFFDRSPSAFRSIVTF 137

  Fly    64 YRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEE 128
            ...|||....::|...|:|||.:||::...:|.||.....:.::.|.     ::|.:|.|   |.
Zfish   138 LAAGKLRLLREMCALSFQEELSYWGVEEASLEWCCLRKLRLRQEEQR-----ERLRLEEE---EA 194

  Fly   129 QIARLFGFEEALS-----NGELN-CWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFC 187
            ::......|||.:     .|.|: |...::.    |.:.|.|....||.|.:||.|:.::.::.|
Zfish   195 ELTSPHSCEEAPAVGSPEEGRLSGCMHSLRD----MVENPHSGIPGKIFACLSVVFVAITAVTLC 255

  Fly   188 LKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTS 252
            :.|.|..|
Zfish   256 VSTMPDLR--------------------------------------------------------- 263

  Fly   253 YSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAF 317
                                                   ||:..|...:|.:.           .
Zfish   264 ---------------------------------------EEEERGECSQRCYN-----------I 278

  Fly   318 FYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY-TDVMQRMG----------- 370
            |.:|.||..||.:|.::|.|.:.:...|:::|:||||..|.|.:| |.::..|.
Zfish   279 FVLETVCVGWFSLEFLLRFIQTQSKCTFLRTPLNIIDVVAILPYYITLIVDSMSVGDRPAGSGNN 343

  Fly   371 --EYTGLLEAFSIVRIMRLF---KLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAY 430
              |..||:  ..::|.:|:|   :|.|||.||:.|..|.:...:|..||:.||.:.:..|:.|.:
Zfish   344 YLEKVGLV--LRVLRALRIFYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLCVAMALFSPLVF 406

  Fly   431 YAEKLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIV 495
            .||. :.....:|.|||...|||:::||||||||:.|::.||..|.....|:|:|.:|.||.
Zfish   407 LAES-ELGAKQEFTSIPGSYWWAVISMTTVGYGDMVPRSIPGQVVALSSILSGILLMAFPVT--- 467

  Fly   496 SNFSMFYSHTQARSKLPKKRRRVLPVEQPRRKR-EPTAPHRGRTNAIKQTPPTGPGLVAGGVVPV 559
               |:|  ||.:||.|..|.      ||.|..| :|.:....::...:.:..|...:  .|:...
Zfish   468 ---SIF--HTFSRSYLELKE------EQNRATRHKPDSQDSTKSQNSEDSQDTDSSI--HGITET 519

  Fly   560 GAGGPGLGGHAVGHSAAGAPMFK 582
            .|.. .|...:|..::.|||..:
Zfish   520 TAVS-ALHRRSVAVASQGAPQLR 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	38/99 (38%)
		BTB_2	7..97	CDD:280393	37/97 (38%)
		Ion_trans	307..506	CDD:278921	71/215 (33%)
		Ion_trans_2	<449..499	CDD:285168	21/49 (43%)
kcng2	XP_690900.2	BTB	72..172	CDD:197585	37/98 (38%)
		BTB_2	73..171	CDD:280393	37/97 (38%)
		Ion_trans	273..481	CDD:278921	76/229 (33%)
		Ion_trans_2	<416..475	CDD:285168	29/66 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.900