Protein Alignment Shawl and kcng4a

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_001103499.1
• Gene: kcng4a / 561003
• ZFINID: ZDB-GENE-050419-11
• Length: 538
• Species: Danio rerio
• Alignment Length: 627
• Identity: 159/627 - (25%)
• Similarity: 231/627 - (36%)
• Gaps: 207/627 - (33%)

  Fly     8 ILNVSGIRYETYKATLKKIPATRLSRL-----TEALA----NYDPVLNEYFFDRHPGVFTQILNY 63
            ::||.|.||....:||::.|.|||.||     .|.:|    :||...:|:||||.|..|..|||:
Zfish    62 LINVGGNRYTFPWSTLEQFPLTRLGRLKPCSSPEEIARVCDDYDEARHEFFFDRSPNAFRVILNF 126

  Fly    64 YRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEE 128
            ...|||....::|.....|||.:||::...:|.||      .|.....|               |
Zfish   127 LAAGKLRLLREMCALSLHEELNYWGVEMTYMERCC------KRKMYTRL---------------E 170

  Fly   129 QIARLFGFEEALSNGELNC--------WQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVIS 185
            ::|.|...||......|..        :::...::..|.:.|.|....|:.|..||..:.::|||
Zfish   171 EVAELERREEERRQRNLQLRPPIVETRYRKFMNQLRDMVENPQSGVPGKVFACFSVLMVAITVIS 235

  Fly   186 FCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNY 250
            .|:.|.|..|
Zfish   236 LCISTMPDLR------------------------------------------------------- 245

  Fly   251 TSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHE 315
                                                     ||:..|           ...|..:
Zfish   246 -----------------------------------------EEENRG-----------VCSQKCQ 258

  Fly   316 AFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY---------TDVMQRMGE 371
            ..|.:|.||..||.:|.::|.:.:.:..||::.|:||||..|.|.:|         .|..:|...
Zfish   259 HMFIIETVCVAWFSLEFLLRFVQARSKLQFLRGPLNIIDAMAILPYYVSLVVDEKPNDENERPSG 323

  Fly   372 YTGLLEAFSIV-------RIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLA 429
            ..|.|:...:|       ||:.:.:|.|||.||:.|..|.:.|.:|..||:.||.:.:..|:.|.
Zfish   324 GKGYLDKLGLVLRILRALRILYVMRLARHSLGLQTLGLTVRRSTREFGLLLLFLCVAVTLFSPLV 388

  Fly   430 YYAEK----LQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALP 490
            :.||.    :||     |.|||...||||::||||||||:.|::.||..|.....|:|:|.:|.|
Zfish   389 HLAESELTGVQD-----FSSIPASYWWAIISMTTVGYGDMVPRSIPGQVVALSSILSGILIMAFP 448

  Fly   491 VPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQT--------PPT 547
            ...|...||..|..              |..|..|..:|..|.....|..:::.        ||
Zfish   449 ATSIFHMFSRSYQE--------------LKQEHDRLFKEECAAAAAATTGLEEEQDGGWVAFPP- 498

  Fly   548 GPGLV-------AGGVVPVGAGGPGLGGHAVGHS----AAGA 578
             |.||       ||....:..  .|.||...|::    .|||
Zfish   499 -PRLVLTPDTETAGSCEDLSL--LGNGGETSGNNKHPLPAGA 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	38/99 (38%)
		BTB_2	7..97	CDD:280393	37/97 (38%)
		Ion_trans	307..506	CDD:278921	75/218 (34%)
		Ion_trans_2	<449..499	CDD:285168	22/49 (45%)
kcng4a	NP_001103499.1	BTB	63..169	CDD:197585	40/111 (36%)
		BTB_2	63..160	CDD:280393	37/96 (39%)
		Ion_trans	261..464	CDD:278921	74/221 (33%)
		Ion_trans_2	376..458	CDD:285168	35/86 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900