Protein Alignment Shawl and kcnk2a

DIOPT Version :10

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: XP_021323122.1
• Gene: kcnk2a / 559728
• ZFINID: ZDB-GENE-061226-2
• Length: 426
• Species: Danio rerio
• Alignment Length: 291
• Identity: 54/291 - (18%)
• Similarity: 102/291 - (35%)
• Gaps: 99/291 - (34%)

  Fly   282 INGSILNEFIEEKIL---------GHNGRRKHGWIETYGQPHEAFFYVELVCNVWFFIEVIIRLI 337
            :|.|.|.:.:::.:|         ||.......|.               :.:.:||...:|..|
Zfish   107 VNTSELEDLVKQVVLAIRAGVNPSGHPSNESSMWD---------------LSSSFFFAGTVITTI 156

  Fly   338 ----VSPN---------LWQFIKSPVNIIDFTATLSFYTDVMQRMGEYTGLLEAFSIVRIMRLF- 388
                |||:         ::..:..|:           :..::..:|:..|.:....|.::.::|
Zfish   157 GFGNVSPHTEGGRIFCIIYALLGIPL-----------FGFLLAGVGDQLGTIFGKGIAKVEKMFV 210

  Fly   389 KLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKSIP-----L 448
            |.......:|:            |..|.|::.|.:.|.:|          |...|:.|.     .
Zfish   211 KWNVSQTKIRV------------TSTVLFILFGCLLFVAL----------PALIFQHIEGWSALE 253

  Fly   449 GLWWAIVTMTTVGYGDVA-------------PKTYPGMFVGALCALAGVLTIALPVPVIVS---- 496
            .:::.::|:||:|:||..             |..:..:.|| |...|.||::......::|
Zfish   254 SIYFVVITLTTIGFGDFVAGGSEIEYLDYYKPIVWFWILVG-LAYFAAVLSMIGDWLRVISKKTK 317

  Fly   497 -NFSMFYSH----TQARSKLPKKRRRVLPVE 522
             ....|.:|    |...|...|:.||.|.||
Zfish   318 EEVGEFRAHAAEWTANVSAEFKETRRRLSVE 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB_Shaw-like	4..115	CDD:349723
		Ion_trans	307..506	CDD:459842	39/239 (16%)
kcnk2a	XP_021323122.1	Ion_trans_2	<136..194	CDD:462301	10/83 (12%)
		Ion_trans_2	232..310	CDD:462301	18/88 (20%)