Protein Alignment Shawl and Kcng4

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_001100905.1
• Gene: Kcng4 / 307900
• RGDID: 1308553
• Length: 506
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 146/574 - (25%)
• Similarity: 222/574 - (38%)
• Gaps: 160/574 - (27%)

  Fly     7 IILNVSGIRYETYKATLKKIPATRLSRL---------TEALANYDPVLNEYFFDRHPGVFTQILN 62
            |::||.|.||....:||...|.:|||||         |:...:||....|:||||:|..|..|::
  Rat    60 ILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSYEEITQLCDDYDENSQEFFFDRNPSAFGVIVS 124

  Fly    63 YYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTE 127
            :...|||....::|...|.|||.:||::...:|.||            ...:|.||:...|...|
  Rat   125 FLAAGKLVLLREMCALSFREELSYWGIEEANLERCC------------LRKLLKKLEEAAELRRE 177

  Fly   128 EQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHP 192
            |...|....:...|..:.:.|.|...::..|.::|.|....|:.|.:||.|:..:.:|.|:.|.|
  Rat   178 EAAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMP 242

  Fly   193 GFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGN 257
            .||.:                    :..||..:...|
  Rat   243 DFRAE--------------------EDKGECARKCYY---------------------------- 259

  Fly   258 FTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVEL 322
                                                                       .|.||.
  Rat   260 -----------------------------------------------------------IFVVET 265

  Fly   323 VCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDV------------------MQRM 369
            :|..||.:|..:|.:.:||..||.:.|:|:||..|...:|..:                  ::::
  Rat   266 ICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDESPEAGERPSGSSYLEKV 330

  Fly   370 GEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEK 434
            |....:|.|..|:.:||   |.|||.||:.|..|.:..|:|..||:.||.:.:..|:.|.|.||.
  Rat   331 GLVLRVLRALRILYVMR---LARHSLGLQTLGLTVRRCAREFGLLLLFLGVAVTLFSPLVYVAEN 392

  Fly   435 LQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFS 499
             :.....:|.|||...||||::||||||||:.|::.||..|.....|:|:|.:|.|...|...||
  Rat   393 -ESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFS 456

  Fly   500 MFYSHTQARSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQTPP---TGPG 550
            ..|...:...:..:.|.|       |.:...:|..|...:.:....|   |.||
  Rat   457 HSYLELKREQEQVQARLR-------RLQNNNSASERELLSDVDDLAPEDLTSPG 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	37/100 (37%)
		BTB_2	7..97	CDD:280393	36/98 (37%)
		Ion_trans	307..506	CDD:278921	72/216 (33%)
		Ion_trans_2	<449..499	CDD:285168	22/49 (45%)
Kcng4	NP_001100905.1	BTB	60..167	CDD:197585	39/118 (33%)
		BTB_2	60..159	CDD:280393	36/98 (37%)
		Ion_trans	260..463	CDD:278921	72/206 (35%)
		Ion_trans_2	397..457	CDD:285168	27/59 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900