Protein Alignment Shawl and Kcnf1

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_001162575.1
• Gene: Kcnf1 / 298908
• RGDID: 631414
• Length: 505
• Species: Rattus norvegicus
• Alignment Length: 603
• Identity: 168/603 - (27%)
• Similarity: 245/603 - (40%)
• Gaps: 172/603 - (28%)

  Fly     7 IILNVSGIRYETYKATLKKIPATRLSRLTEALA-----------NYDPVLNEYFFDRHPGVFTQI 60
            |::||.|:|...|...|.:.|.|||:.|...||           :|||...|::|||.|..|..:
  Rat    37 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCV 101

  Fly    61 LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLA-----ILDKLDI 120
            :..|..|::|....:|...|:.|::||.:|...::.||.|..|..|:....:|     |||.|.:
  Rat   102 IEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGV 166

  Fly   121 ENEKPTEEQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVIS 185
            :                  .:.|.   |:|.:..:|...::|.||..|::||.:|...|.||.:.
  Rat   167 D------------------AAEGR---WRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVV 210

  Fly   186 FCLKTHPGFR-VDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTN 249
            .|:.|.|..: ||
  Rat   211 MCMGTIPELQVVD---------------------------------------------------- 223

  Fly   250 YTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPH 314
                |.||                                           |.:|..:|.
  Rat   224 ----SEGN-------------------------------------------RVEHPTLEN----- 236

  Fly   315 EAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY-----TDVMQRMGEYTG 374
                 ||..|..||.:|.::||..|||...|..|.:||:|..|.|.||     |.:..||.|.|.
  Rat   237 -----VETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTN 296

  Fly   375 L---LEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQ 436
            :   ::|..|:||.|:|||.|||.||:.|.:..|.|.|||.||:.:|.:||..|::|.|..|  |
  Rat   297 VQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTME--Q 359

  Fly   437 DNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMF 501
            .:|:..|||||...||||:|||||||||:.|||..|....|:..|.||:.||||:..|::||..:
  Rat   360 SHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRY 424

  Fly   502 YSHTQARSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQTPPTGPGLVAGGVVPVGAGGPGL 566
            |:..:......|....::.:.....:.:|    .|..:.:...||.          |....||..
  Rat   425 YNKQRVLETAAKHELELMELNSSSAESKP----GGSRSDLDTLPPE----------PAAREGPSW 475

  Fly   567 GGH-AVGHSAAGAPMFKD 583
            |.. .:.||....|:..:
  Rat   476 GSRLKLSHSDTFIPLLTE 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	33/102 (32%)
		BTB_2	7..97	CDD:280393	32/100 (32%)
		Ion_trans	307..506	CDD:278921	90/206 (44%)
		Ion_trans_2	<449..499	CDD:285168	27/49 (55%)
Kcnf1	NP_001162575.1	BTB	37..147	CDD:197585	36/109 (33%)
		BTB	37..138	CDD:295341	32/100 (32%)
		Ion_trans	234..429	CDD:278921	90/206 (44%)
		Ion_trans_2	343..412	CDD:285168	36/70 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D331021at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910