Protein Alignment Shawl and Kcna10

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_001074609.1
• Gene: Kcna10 / 242151
• MGIID: 3037820
• Length: 511
• Species: Mus musculus
• Alignment Length: 557
• Identity: 171/557 - (30%)
• Similarity: 255/557 - (45%)
• Gaps: 153/557 - (27%)

  Fly     2 DGENRIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYRT 66
            :|..|:|:|::|:|:||...||.:.|.|.|....:.:..:|.:.|||||||:...|..||.||::
Mouse    83 EGNQRVIINIAGLRFETQLRTLNQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQS 147

  Fly    67 -GKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEEQI 130
             ||:..|.:|...:|.:|:.|:.|.|..::.        .|:.:..:.     |.|...||
Mouse   148 GGKIRRPANVPIDVFADEISFYELGSEAMDQ--------FREDEGFIK-----DPETLLPT---- 195

  Fly   131 ARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPGFR 195
                           |.:.|   :.|.:|:.|.||:.|:.||.:||..:.:|:..|||:|.|.||
Mouse   196 ---------------NDFHR---QFWLLFEYPESSSAARGVAVVSVLVVVISITIFCLETLPEFR 242

  Fly   196 VDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGNFTA 260
            .|                               .....:..||.:       ||.|..|...||
Mouse   243 ED-------------------------------RELKVVRDPSIN-------TNKTGLSQTMFT- 268

  Fly   261 SGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVELVCN 325
                                                                  :.||.||..|.
Mouse   269 ------------------------------------------------------DPFFMVESTCI 279

  Fly   326 VWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDVMQRMGEYT----------GLLEAFS 380
            |||..|:::|.:|.|:...|.|:.:||||..:.:.::..::..:.:.|          .:|....
Mouse   280 VWFTFELVLRFVVCPSKTDFFKNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIR 344

  Fly   381 IVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKS 445
            :||:.|:|||:|||.||:||..|.|||.:||.||:|||.:|::.|:|..|:||  .|.|::.|.|
Mouse   345 LVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE--VDEPESHFSS 407

  Fly   446 IPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFY---SHTQA 507
            ||.|.|||:||||||||||:.|.|..|..||.|||:|||||||||||||||||:.||   :..:.
Mouse   408 IPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEE 472

  Fly   508 RSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQT 544
            :..:|.:..::|         .......|.|.::.:|
Mouse   473 KPNIPGELDKIL---------NSMGSRMGSTESLNKT 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	33/92 (36%)
		BTB_2	7..97	CDD:280393	33/90 (37%)
		Ion_trans	307..506	CDD:278921	97/211 (46%)
		Ion_trans_2	<449..499	CDD:285168	38/49 (78%)
Kcna10	NP_001074609.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..44
		BTB_2	88..179	CDD:280393	33/98 (34%)
		BTB	88..171	CDD:197585	31/82 (38%)
		Ion_trans	267..467	CDD:278921	99/256 (39%)
		Ion_trans_2	382..458	CDD:285168	48/77 (62%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	421..426		4/4 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	489..511		3/12 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810