Protein Alignment Shawl and Kcng1

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_001074603.1
• Gene: Kcng1 / 241794
• MGIID: 3616086
• Length: 514
• Species: Mus musculus
• Alignment Length: 554
• Identity: 150/554 - (27%)
• Similarity: 234/554 - (42%)
• Gaps: 171/554 - (30%)

  Fly     2 DGENRIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVL----------NEYFFDRHPGV 56
            |...:||:||.||:|.....||.:.|.|||.:| :|..|:|.:|          ||:||||:||.
Mouse    60 DRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQL-KACTNFDDILSVCDDYDVTCNEFFFDRNPGA 123

  Fly    57 FTQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTY---------SIHRDTQNTL 112
            |..||.:.|.|||....::|...|:|||.:||:..:.::.||...|         .:.|:.:.
Mouse   124 FGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMMEREEEE-- 186

  Fly   113 AILDKLDIENEKPTEEQIARLFGFEEALSNGELN-CWQRIKPKIWAMFDEPSSSTGAKIVAGMSV 176
            ..||..|.|:|.|             :.|.|.|: |.:|::.    |.:.|.|....|:.|.:||
Mouse   187 EPLDSEDQESEGP-------------SASEGRLSRCMRRLRD----MVERPHSGLPGKVFACLSV 234

  Fly   177 FFIFVSVISFCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSI 241
            .|:.|:.::..:.|.|..|.:
Mouse   235 LFVTVTAVNLSVSTLPSLREE-------------------------------------------- 255

  Fly   242 GPTFRVTNYTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGW 306
                             ...||.:.:.                             ||
Mouse   256 -----------------EEQGQCSQMC-----------------------------HN------- 267

  Fly   307 IETYGQPHEAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDVM----- 366
                      .|.||.||..||.:|.::|.|.:|:.:.|::||:.:||..|.|.:|..::
Mouse   268 ----------VFIVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAA 322

  Fly   367 -QRMGEYTG---------LLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLG 421
             .|....||         :|.....:||:.:.:|.|||.||:.|..|.:...:|..||:.||.:.
Mouse   323 SSRRKPSTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVA 387

  Fly   422 IVFFASLAYYAE-KLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVL 485
            |..||.|.|..| ::.|:|  :|.|||...|||::|||||||||:.|::.||..|.....|:|:|
Mouse   388 IALFAPLLYVIENEMADSP--EFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGIL 450

  Fly   486 TIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVL 519
            .:|.||.      |:|::.:::..:|.:::.|||
Mouse   451 LMAFPVT------SIFHTFSRSYLELKQEQERVL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	41/101 (41%)
		BTB_2	7..97	CDD:280393	40/99 (40%)
		Ion_trans	307..506	CDD:278921	74/214 (35%)
		Ion_trans_2	<449..499	CDD:285168	22/49 (45%)
Kcng1	NP_001074603.1	BTB_POZ_KCNG1_2	60..173	CDD:349728	44/113 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	180..205		8/39 (21%)
		Ion_trans	227..471	CDD:395416	87/358 (24%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	424..429		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900