Protein Alignment Shawl and Kcnv2

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_899002.1
• Gene: Kcnv2 / 240595
• MGIID: 2670981
• Length: 562
• Species: Mus musculus
• Alignment Length: 560
• Identity: 133/560 - (23%)
• Similarity: 215/560 - (38%)
• Gaps: 164/560 - (29%)

  Fly     1 MDGEN-------RIILNVSGIRYETYKATLKKIPATRLSRLTEALA---------NYDPVLNEYF 49
            :||.|       .:.:||.|..|......|...|.|||.||..:..         :|:...:|||
Mouse    94 LDGHNDTPAQMSTLKVNVGGHSYLLECCELANYPKTRLGRLATSTTRRGQLGLCDDYEAQTDEYF 158

  Fly    50 FDRHPGVFTQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAI 114
            |||.|.||..|.|:|.:|.|....::|...|.|||.:||:.......||...:...||     .:
Mouse   159 FDRDPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRD-----EL 218

  Fly   115 LDKLDIENE---KPTEEQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSV 176
            .::|.|:.|   :...|:...||        .::..:...:.::|.:.::|.||..||.:...:.
Mouse   219 SEQLKIQRELRAQAQAEEAEELF--------RDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVATN 275

  Fly   177 FFIFVSVISFCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSI 241
            .|:.:||::..|.|       :....|.|. .|.||
Mouse   276 LFVLISVVALALNT-------VEEMQHQAE-QGTGG----------------------------- 303

  Fly   242 GPTFRVTNYTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGW 306
                                                                             
Mouse   304 ----------------------------------------------------------------- 303

  Fly   307 IETYGQPHEAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY--------- 362
                |.|.....:||::|..:|.:|.::||..:|||.:|.:|.:|::|..|.|.||
Mouse   304 ----GDPRPILEHVEMLCVAFFTLEFLLRLASTPNLQRFARSALNLVDLVAILPFYLQLLLECFT 364

  Fly   363 ---------------TDVMQRMGEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELT 412
                           .:.:.|:|:...:|....::||.|:.||.|||.|||....|.:...:::.
Mouse   365 SEDQRHNKDSPREHDLETVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVG 429

  Fly   413 LLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGA 477
            .|:.|:.:||..|::..|..|  .|.|...|.||....|||.|:::||||||:.|:|:.|.....
Mouse   430 CLMLFITMGIFSFSAAVYSVE--HDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAF 492

  Fly   478 LCALAGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRR 517
            ||...|::...:|:.::.:.||.:||..:|......:|.|
Mouse   493 LCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRER 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	34/100 (34%)
		BTB_2	7..97	CDD:280393	33/98 (34%)
		Ion_trans	307..506	CDD:278921	68/222 (31%)
		Ion_trans_2	<449..499	CDD:285168	17/49 (35%)
Kcnv2	NP_899002.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34
		BTB	107..198	CDD:197585	32/90 (36%)
		BTB	107..198	CDD:295341	32/90 (36%)
		Ion_trans	305..521	CDD:278921	67/217 (31%)
		Ion_trans_2	434..509	CDD:285168	28/76 (37%)
		Selectivity filter. /evidence=ECO:0000250	474..479		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910