Protein Alignment Shawl and shl-1

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_500975.2
• Gene: shl-1 / 177400
• WormBaseID: WBGene00022240
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 170/553 - (30%)
• Similarity: 253/553 - (45%)
• Gaps: 149/553 - (26%)

  Fly     4 ENRIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYRTGK 68
            :.::.:|:||.|:||:|.||:|.|.|.|.. .|....||....||||||.|.:|..||.:|||||
 Worm    45 DEKLAINISGRRFETWKNTLEKFPETLLGS-NEKEFFYDEDTGEYFFDRDPDIFRHILTFYRTGK 108

  Fly    69 LHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEEQIARL 133
            ||||...|...::|||.|:|:..:.:..||:..|.                 :.::..:|::.
 Worm   109 LHYPRHECLVAYDEELSFFGIMPDLISDCCYEDYK-----------------DKKRENQERLQ-- 154

  Fly   134 FGFEEALSNGELNCWQ-RIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPGFRVD 197
               ||.:.|.:::..: .:|.|:||.|:.|.:::.|.:...:..|||.|||:...::|
 Worm   155 ---EERVENADISTLKLSLKEKMWAAFENPHTTSIALVFYYVIGFFIAVSVMCNIVET------- 209

  Fly   198 LPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGNFTASG 262
            :|.|..|
 Worm   210 IPCGYED---------------------------------------------------------- 216

  Fly   263 QATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPH-EAFFYVELVCNV 326
                                |.|:                      |.|:.: |.||.::..|.:
 Worm   217 --------------------NVSV----------------------TCGEAYEEQFFVIDTACVI 239

  Fly   327 WFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTD-VMQRMGEYTGLLEAFSIVRIMRLFKL 390
            .|.||..:|||.:|:..:|::|.:::||..|.:.:|.. |:....:.:||.....:.|:.|:||.
 Worm   240 IFTIEYFLRLISAPDRIKFMRSIMSVIDVIAIMPYYVSLVLTDNKDVSGLFVTLRVFRVFRIFKF 304

  Fly   391 TRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKSIPLGLWWAIV 455
            :|||.|||||.:|.|:.|.||..|||.|.:.|:.||::.|||||..|  ..:|.|||...|:.||
 Worm   305 SRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATIMYYAEKKVD--ATRFTSIPSAFWYTIV 367

  Fly   456 TMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQA--RSKLPKKRR-- 516
            |:||:||||:.|.|..|..||.:|:|:|||.|||||||||||||..|...|.  :.|..||.|
 Worm   368 TLTTLGYGDMVPSTIMGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQKKARLA 432

  Fly   517 RVLPVEQP------RRKREPTAPHRGRTNAIKQ 543
            |:..|:..      .:||    .|..|..|.:|
 Worm   433 RIRIVKNASGLALFNKKR----AHEARMLAFEQ 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	42/91 (46%)
		BTB_2	7..97	CDD:280393	41/89 (46%)
		Ion_trans	307..506	CDD:278921	90/200 (45%)
		Ion_trans_2	<449..499	CDD:285168	31/49 (63%)
shl-1	NP_500975.2	BTB_POZ	6..149	CDD:365784	44/121 (36%)
		Ion_trans	187..416	CDD:366146	103/337 (31%)
		DUF3399	460..528	CDD:371777	1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810