Protein Alignment Shawl and shw-1

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_001022089.1
• Gene: shw-1 / 174331
• WormBaseID: WBGene00008819
• Length: 619
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 290/568 - (51%)
• Similarity: 372/568 - (65%)
• Gaps: 95/568 - (16%)

  Fly     1 MDGENRIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYR 65
            ||.|:|:||||.|||:|||...|||||||||||||..||||||||||||||||||||:.||||||
 Worm    97 MDTEHRVILNVGGIRHETYSHVLKKIPATRLSRLTPNLANYDPVLNEYFFDRHPGVFSMILNYYR 161

  Fly    66 TGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEEQI 130
            ||||||||:||||||||||||||||:||||||||.||:.|||||:|||:::.||::.:.||:|:|
 Worm   162 TGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRDTQDTLAVIESLDLDGDPPTQEEI 226

  Fly   131 ARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPGFR 195
            |:.||:|:....|.::.|||:||::||:||||.||..|::::.:::.|:.:|::.|||||||.||
 Worm   227 AKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVISVVNIIFVIISIVCFCLKTHPSFR 291

  Fly   196 VDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGNFTA 260
            :                                        |...|..|.          |||:|
 Worm   292 I----------------------------------------PDIDISTTM----------GNFSA 306

  Fly   261 SGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVELVCN 325
            .                    :||..:|.....|              |..:.|.:||||||:.|
 Worm   307 P--------------------LNGVQMNNIYVGK--------------TATRAHPSFFYVELLSN 337

  Fly   326 VWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTD-VMQR--MGEYTGLLEAFSIVRIMRL 387
            :||..|.:.|::..||:..|:::|||:|||.||:|||.| .:.|  .|.....:|.|||:||:||
 Worm   338 IWFSGEFLTRMVFCPNVATFLRTPVNLIDFIATVSFYIDWALDRTLSGSNRDSVEFFSIIRILRL 402

  Fly   388 FKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKSIPLGLWW 452
            ||||:||.||:|||.||||||:||.|||||::||||.||:|.||||:::.|.:|||.|||:||||
 Worm   403 FKLTQHSTGLKILIQTFKASAQELFLLVFFVLLGIVIFAALVYYAERVEHNEENQFSSIPVGLWW 467

  Fly   453 AIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRR 517
            |::|:.|:|:||:.|:|..|..||::|||.||||||||||||||||:|||||.||||||||||||
 Worm   468 AVITICTIGFGDLVPQTSLGRLVGSVCALMGVLTIALPVPVIVSNFAMFYSHAQARSKLPKKRRR 532

  Fly   518 VLPVEQPRRKREPTAPHRGR-TNAIKQTPPTGPGLVAGGVVPVGAGGP 564
            ||   ||...:    |..|| |.|:..:..|..|.|:||......|||
 Worm   533 VL---QPHEIK----PVVGRSTTAVMISALTQRGPVSGGGSNPSDGGP 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	79/91 (87%)
		BTB_2	7..97	CDD:280393	77/89 (87%)
		Ion_trans	307..506	CDD:278921	119/201 (59%)
		Ion_trans_2	<449..499	CDD:285168	33/49 (67%)
shw-1	NP_001022089.1	BTB_Shaw-like	100..211	CDD:349723	93/110 (85%)
		Ion_trans	264..521	CDD:366146	142/340 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160124
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	619	1.000	Inparanoid score	I483
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D331021at33208
OrthoFinder	1	1.000	-	-		FOG0000990
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.000