Protein Alignment Shawl and Kcna3

DIOPT Version :9

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_032444.2
• Gene: Kcna3 / 16491
• MGIID: 96660
• Length: 528
• Species: Mus musculus
• Alignment Length: 516
• Identity: 164/516 - (31%)
• Similarity: 239/516 - (46%)
• Gaps: 147/516 - (28%)

  Fly     3 GENRIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYRT- 66
            || |:::|:||:|:||...||.:.|.|.|......:..:||:.|||||||:...|..||.||::
Mouse    56 GE-RVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSG 119

  Fly    67 GKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEEQIA 131
            |::..|.:|...:|.||:.|:.|....:|.        .|:.:..|.       |.|:|...:
Mouse   120 GRIRRPVNVPIDIFSEEIRFYQLGEEAMEK--------FREDEGFLR-------EEERPLPRR-- 167

  Fly   132 RLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPGFR- 195
                           .:||   ::|.:|:.|.||..|:.:|.:||..|.:|::.|||:|.|.||
Mouse   168 ---------------DFQR---QVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRD 214

  Fly   196 -VDLPSG----AHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSS 255
             .|.|:.    ..:|......|.|.|.....:|
Mouse   215 EKDYPASPSQDVFEAANNSTSGAPSGASSFSDP-------------------------------- 247

  Fly   256 GNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYV 320
                                                                         ||.|
Mouse   248 -------------------------------------------------------------FFVV 251

  Fly   321 ELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY----TDVMQRMGE-----YTGLL 376
            |.:|.:||..|:::|....|:...|.::.:|:||..|.:.::    |::.:|.|.     ...:|
Mouse   252 ETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAIL 316

  Fly   377 EAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDN 441
            ....:||:.|:|||:|||.||:||..|.|||.:||.||:|||.:|::.|:|..|:||  .|:|.:
Mouse   317 RVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE--ADDPSS 379

  Fly   442 QFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFY 502
            .|.|||...|||:||||||||||:.|.|..|..||:|||:|||||||||||||||||:.||
Mouse   380 GFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	34/92 (37%)
		BTB_2	7..97	CDD:280393	34/90 (38%)
		Ion_trans	307..506	CDD:278921	95/205 (46%)
		Ion_trans_2	<449..499	CDD:285168	37/49 (76%)
Kcna3	NP_032444.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32
		BTB	59..153	CDD:197585	35/101 (35%)
		BTB_2	59..150	CDD:280393	34/98 (35%)
		Ion_trans	243..443	CDD:278921	96/293 (33%)
		Ion_trans_2	357..434	CDD:285168	48/78 (62%)
		Selectivity filter. /evidence=ECO:0000250	397..402		4/4 (100%)
		PDZ-binding. /evidence=ECO:0000250	526..528

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810