Protein Alignment Shawl and kcna1

DIOPT Version :10

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: XP_004912857.1
• Gene: kcna1 / 100492822
• XenbaseID: XB-GENE-991584
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 550
• Identity: 166/550 - (30%)
• Similarity: 250/550 - (45%)
• Gaps: 152/550 - (27%)

  Fly     6 RIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYRT-GKL 69
            |:::||:|:|:||...||.:.|.|.|....:.:..:||:.|||||||:...|..||.||:: |:|
 Frog    35 RVVINVAGLRFETQLKTLSQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRL 99

  Fly    70 HYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEEQIARLF 134
            ..|.:|...:|.||::|:.|....:|.        .|:.:..:.       |.|:|..|
 Frog   100 RRPVNVPLDMFSEEIKFYELGEEAMEK--------FREDEGFIR-------EEERPLPE------ 143

  Fly   135 GFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPGFRVDLP 199
                          :..:.::|.:|:.|.||..|:|:|.:||..|.:|::.|||:|.|..:.:..
 Frog   144 --------------KEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVIFCLETLPELKDERI 194

  Fly   200 SGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYT-SYSSGNFTASGQ 263
            ...                                           ||.|.| .|.|..||
 Frog   195 FSR-------------------------------------------RVNNSTVFYKSNIFT---- 212

  Fly   264 ATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVELVCNVWF 328
                                                               :.||.||.:|.:||
 Frog   213 ---------------------------------------------------DPFFVVETLCIIWF 226

  Fly   329 FIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDVMQRMGEYTG-----------LLEAFSIV 382
            ..|:::|....|:..:|.|:.:|.||..|.:.::..:...|.|..|           :|....:|
 Frog   227 SFELVVRFFACPSKPEFFKNIMNFIDIVAIIPYFITLGTEMAEQEGPQKGEQATSLAILRVIRLV 291

  Fly   383 RIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKSIP 447
            |:.|:|||:|||.||:||..|.|||.:||.||:|||.:|::.|:|..|:||..:|  ::.|.|||
 Frog   292 RVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEED--ESHFASIP 354

  Fly   448 LGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQARSKLP 512
            ...|||:|:||||||||:.|.|..|..||:|||:|||||||||||||||||:.|| |.:...
 Frog   355 DAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEG--- 415

  Fly   513 KKRRRVLPVEQPRRKREPTAPHRGRTNAIK 542
            :::.::|.|..|....:.....|..:...|
 Frog   416 EEQAQLLHVSTPNLASDSDLSRRSSSTMSK 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB_Shaw-like	4..115	CDD:349723	37/109 (34%)
		Ion_trans	307..506	CDD:459842	95/209 (45%)
kcna1	XP_004912857.1	BTB_POZ	34..160	CDD:453885	44/159 (28%)
		Ion_trans	163..412	CDD:459842	115/349 (33%)