Protein Alignment Shawl and kcnc2

DIOPT Version :10

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: XP_002939991.2
• Gene: kcnc2 / 100489216
• XenbaseID: XB-GENE-1013657
• Length: 598
• Species: Xenopus tropicalis
• Alignment Length: 553
• Identity: 224/553 - (40%)
• Similarity: 300/553 - (54%)
• Gaps: 128/553 - (23%)

  Fly     1 MDGENRIILNVSGIRYETYKATLKKIPATRLSRL--------------TEALANYDPVLNEYFFD 51
            :|...||||||.|.|:|||::|||.:|.|||:.|              .....|.....||:|||
 Frog     4 IDENERIILNVGGTRHETYRSTLKTVPGTRLALLACESQSEQGLDQQTVSGSFNITSRGNEFFFD 68

  Fly    52 RHPGVFTQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILD 116
            ||||||..:||||||||||.|.|||||||||||.|||:|...||||||.||..|||.:..|.|.:
 Frog    69 RHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFE 133

  Fly   117 KLDIENEKPT-----EEQIARLFGFEEAL-SNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMS 175
            ..|:...:|.     ||.:.:....|:.: .:|::..|:|::|::||:|::|.||..|:.:|..|
 Frog   134 TPDLITGEPPPIDEYEEDLGKRLAIEDVVCPDGKVGRWRRLQPRMWALFEDPYSSRAARFIAFAS 198

  Fly   176 VFFIFVSVISFCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGS 240
            :|||.||:.:|||:||..|..
 Frog   199 LFFILVSITTFCLETHEAFNT-------------------------------------------- 219

  Fly   241 IGPTFRVTNYTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHG 305
                  :.|.|.                |:.           ||:.|...||
 Frog   220 ------IINKTE----------------TVN-----------NGTELISLIE------------- 238

  Fly   306 WIETYGQPHEAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDV----- 365
             |||    ..|..|||.||.|||..|.::|:|..|:..:||::.:|||||.|.|.||.:|
 Frog   239 -IET----DPALTYVEGVCVVWFTFEFLVRVIFCPDKLEFIRNLLNIIDFVAILPFYLEVGLSGL 298

  Fly   366 -MQRMGEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLA 429
             .:...:..|.|.....|||:|:||||||..|||:|.||.:||..|..||:.||.||::.||::.
 Frog   299 SSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMI 363

  Fly   430 YYAEKLQDNPDN-------QFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTI 487
            ||||::..:|.:       |||:||:|.|||:|||||:||||:.|:|:.||.|||||||||||||
 Frog   364 YYAERIGASPSDPSASKHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTI 428

  Fly   488 ALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLP 520
            |:||||||:||.|:||...|:.|||:||::.:|
 Frog   429 AMPVPVIVNNFGMYYSLAMAKQKLPRKRKKYIP 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB_Shaw-like	4..115	CDD:349723	69/124 (56%)
		Ion_trans	307..506	CDD:459842	109/211 (52%)
kcnc2	XP_002939991.2	BTB_KCNC2_4	7..129	CDD:349722	68/121 (56%)
		Ion_trans	191..447	CDD:459842	131/350 (37%)