DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Shawl and kcnd1

DIOPT Version :9

Sequence 1:NP_001097131.2 Gene:Shawl / 5740840 FlyBaseID:FBgn0085395 Length:937 Species:Drosophila melanogaster
Sequence 2:XP_031747765.1 Gene:kcnd1 / 100488387 XenbaseID:XB-GENE-6047565 Length:631 Species:Xenopus tropicalis


Alignment Length:513 Identity:163/513 - (31%)
Similarity:232/513 - (45%) Gaps:130/513 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MDGENRIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYR 65
            |..:..:::||||.:::|:|.||.:.|.|.|.. ||....::....||||||.|.:|..|||:||
 Frog    36 MKSDEILVVNVSGRKFQTWKNTLDRYPDTLLGS-TEKDFFFNQDTQEYFFDRDPEMFRHILNFYR 99

  Fly    66 TGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEEQI 130
            |||||||...|...|:|||.|:|:....:..||...|   ||.:                 :|.:
 Frog   100 TGKLHYPRHECIQAFDEELSFYGIIPEIIGDCCLEEY---RDRK-----------------KENL 144

  Fly   131 ARLFGFEEALSNGE--LNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPG 193
            .||....||.:.|:  |......:.::|..|:.|.:||.|.:...::.|||.||||:..::|.| 
 Frog   145 ERLAEDTEAETAGDTPLPPDSTFRQRLWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVP- 208

  Fly   194 FRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGNF 258
                                                    ..||:|                   
 Frog   209 ----------------------------------------CRPPAG------------------- 214

  Fly   259 TASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVELV 323
                              |||....|                       |.|   :.||..::..
 Frog   215 ------------------RLKELPCG-----------------------EKY---NLAFVCMDTA 235

  Fly   324 CNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTD-VMQRMGEYTGLLEAFSIVRIMRL 387
            |.:.|..|.::||..:|:..:|::|.::|||..|.:.||.. ||......:|......:.|:.|:
 Frog   236 CVLIFTFEYLMRLFAAPSRCKFMRSVMSIIDVVAIMPFYIGLVMPENENVSGAFVTLRVFRVFRI 300

  Fly   388 FKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKSIPLGLWW 452
            ||.:|||.|||||.:|.|:.|.||..|:|.|.:.|:.||::.:||||  .....:|.|||...|:
 Frog   301 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEK--GTSKTKFTSIPAAFWY 363

  Fly   453 AIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQARSK 510
            .||||||:||||:.|.|..|...|::|:|:|||.|||||||||||||..|...|...|
 Frog   364 TIVTMTTLGYGDMVPDTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADK 421

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ShawlNP_001097131.2 BTB 7..99 CDD:197585 41/91 (45%)
BTB_2 7..97 CDD:280393 40/89 (45%)
Ion_trans 307..506 CDD:278921 86/199 (43%)
Ion_trans_2 <449..499 CDD:285168 31/49 (63%)
kcnd1XP_031747765.1 BTB_POZ_KCND1 6..143 CDD:349724 46/127 (36%)
Ion_trans 184..415 CDD:395416 103/336 (31%)
DUF3399 445..542 CDD:403174
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X19
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.