Protein Alignment Shawl and kcna3

DIOPT Version :10

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: XP_004910792.1
• Gene: kcna3 / 100145813
• XenbaseID: XB-GENE-1010662
• Length: 526
• Species: Xenopus tropicalis
• Alignment Length: 606
• Identity: 183/606 - (30%)
• Similarity: 270/606 - (44%)
• Gaps: 168/606 - (27%)

  Fly     6 RIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYRT-GKL 69
            |:::|:||:|:||...||.:.|.|.|....:.:..:||:.|||||||:...|..||.||:: |::
 Frog    71 RVVINISGLRFETQLKTLAQFPDTLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRI 135

  Fly    70 HYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEEQIARLF 134
            ..|.:|...:|.||:.|:.|....:|.        .|:.:..:.       |.|:|...
 Frog   136 RRPVNVPIDIFSEEIRFYELGEEAMEK--------FREDEGFIR-------EEERPLPP------ 179

  Fly   135 GFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPGFRVDLP 199
                       |.:||   ::|.:|:.|.||..|:.:|.:||..|.:|::.|||:|.|.||.|
 Frog   180 -----------NEFQR---QVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDD-- 228

  Fly   200 SGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGNFTASGQA 264
                                        :.:..:..||....||         |.|.:||
 Frog   229 ----------------------------KEYSGTALPPGNGTGP---------YISSSFT----- 251

  Fly   265 TPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVELVCNVWFF 329
                                                              :.||.||.:|.:||.
 Frog   252 --------------------------------------------------DPFFVVETLCIIWFS 266

  Fly   330 IEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY----TDVMQRMGE-----YTGLLEAFSIVRIM 385
            .|:::|....|:...|.|:.:||||..|.:.::    |::.:|.|.     ...:|....:||:.
 Frog   267 FELLVRFFACPSKATFCKNIMNIIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVF 331

  Fly   386 RLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKSIPLGL 450
            |:|||:|||.||:||..|.|||.:||.||:|||.:|::.|:|..|:||  .|:|.:.|.|||...
 Frog   332 RIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE--ADDPSSGFNSIPDAF 394

  Fly   451 WWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKR 515
            |||:||||||||||:.|.|..|..||:|||:|||||||||||||||||:.|| |.:...:
 Frog   395 WWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGE----- 453

  Fly   516 RRVLPVEQPRRKREPTAPHRGRTNAIKQTPPTGPGLVAGGVVPVGAG-GPGLGGHAVGHSAAGAP 579
                  ||.:.....:..|......:|:. .:...|.....:.:..| .||             |
 Frog   454 ------EQAQYLHVGSCQHLSSNEDLKKA-RSNSSLSKSEYMVIEEGVSPG-------------P 498

  Fly   580 MFKDAFGGAKIGTVNVNGVNV 600
            ..:.||......|.|.|.||:
 Frog   499 FKQPAFKTGNCTTNNPNCVNI 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB_Shaw-like	4..115	CDD:349723	36/109 (33%)
		Ion_trans	307..506	CDD:459842	98/207 (47%)
kcna3	XP_004910792.1	BTB_POZ	70..196	CDD:453885	45/159 (28%)
		Ion_trans	199..449	CDD:459842	120/346 (35%)