Protein Alignment Shawl and kcng1

DIOPT Version :10

• Sequence 1: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_001096675.1
• Gene: kcng1 / 100125206
• XenbaseID: XB-GENE-1011042
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 571
• Identity: 151/571 - (26%)
• Similarity: 238/571 - (41%)
• Gaps: 167/571 - (29%)

  Fly     2 DGENRIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVL----------NEYFFDRHPGV 56
            |.::..|:||.|.||.....||::.|.|||.:| :..:|:|.:|          ||:||||:||.
 Frog    59 DRKHHAIINVGGFRYLLPWTTLEEFPLTRLGQL-KLCSNFDEILSICDDYDVTCNEFFFDRNPGA 122

  Fly    57 FTQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIE 121
            |..||.:.:.|||....::|...|:|||.:||::.:.:|.||...|....:....|.:.::..||
 Frog   123 FRTILTFLQVGKLRLLREMCALSFQEELLYWGIEEDNLEWCCKRRYIQKMEEFAELNLREEELIE 187

  Fly   122 NEKPTEEQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISF 186
            ||..:|.:           ...:|:...|   .:..|.::|.|....||.|.:||.|:.::.::.
 Frog   188 NENASEPE-----------DESKLDICMR---HLGDMVEKPQSGLPGKIFACLSVLFVTITAVNL 238

  Fly   187 CLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYT 251
            .:.|.|..|.:...|                                             |.:..
 Frog   239 SISTMPDLREEEEKG---------------------------------------------VCSKM 258

  Fly   252 SYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEA 316
            .|:
 Frog   259 CYN-------------------------------------------------------------- 261

  Fly   317 FFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY--------TDVMQRMGEYT 373
            .|.||.||..||.:|.::|.|.:|:.:.||:.|:|:||..|.|.:|        :|..::.|...
 Frog   262 IFIVESVCVGWFSLEFLLRFIQAPSKFAFIRRPLNLIDIVAILPYYITLVVDNTSDGQKKPGSGN 326

  Fly   374 GLLEAFSIV-------RIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYY 431
            ..|:...:|       ||:.:.:|.|||.||:.|..|.:...:|..||:.||.:.|..||.|.|.
 Frog   327 SYLDKVGLVLRILRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYL 391

  Fly   432 AE-KLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIV 495
            .| ::.|:  .:|.|||...|||::|||||||||:.|::.||..|.....|:|:|.:|.||.
 Frog   392 IENEMADS--QEFTSIPACYWWAVITMTTVGYGDMVPRSIPGQVVALSSILSGILLMAFPVT--- 451

  Fly   496 SNFSMFYSHTQARSKLPKKRRRVLPVEQPR---RKREPTAPHRGRTNAIKQ 543
               |:|  ||.:||.:..|:      ||.|   ||.:.....:.:.::|.|
 Frog   452 ---SIF--HTFSRSYIELKQ------EQERLMCRKAQLLMKTKSQMSSISQ 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shawl	NP_001097131.2	BTB_Shaw-like	4..115	CDD:349723	42/120 (35%)
		Ion_trans	307..506	CDD:459842	75/214 (35%)
kcng1	NP_001096675.1	BTB_POZ_KCNG1_2	59..172	CDD:349728	42/113 (37%)
		Ion_trans	221..461	CDD:459842	89/356 (25%)