Protein Alignment CG34425 and CFAP53

DIOPT Version :9

• Sequence 1: NP_001097683.1
• Gene: CG34425 / 5740837
• FlyBaseID: FBgn0085454
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_659457.2
• Gene: CFAP53 / 220136
• HGNCID: 26530
• Length: 514
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 108/472 - (22%)
• Similarity: 206/472 - (43%)
• Gaps: 58/472 - (12%)

  Fly    18 DRKSLHTQIGLLVNKAKEVTAAELHERSKRLKNMLDEEDKRYEEEFSNTVKNRIDQDIKER-KEH 81
            |.|.|.:.:...:..|.:.....:.||..:|:.:|..|:..|..|..  :|....::.|:| :|.
Human    71 DCKILDSLVRARIKDAVQGFIINIEERRNKLRELLALEENEYFTEMQ--LKKETIEEKKDRMREK 133

  Fly    82 LHAIKEQVAKQQKKFLEEKHIQQVMLDCYEIREALR--HQDLVETKIVQEE--QILENQRKKRRE 142
            ...:||:..|:::.|:.||..||....|.|:|..|.  ||    .|:.:|.  ||..|:...|::
Human   134 TKLLKEKNEKERQDFVAEKLDQQFRERCEELRVELLSIHQ----KKVCEERKAQIAFNEELSRQK 194

  Fly   143 CQQDNYWLELNRRRWAQFDCNQAEENQRRHQMQQQVNHVLAVQVAEHEEKRKAALAERMEDERLI 207
            ..::..:.:|........:..:|:|.:|:.::.:.....|..|:...:.:|:|....:.|:.||:
Human   195 LVEEQMFSKLWEEDRLAKEKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLV 259

  Fly   208 NSLLEEIRLE---EFEKEHQAAPVDQLAYQDELLKEIERKRCARLAEWEAEK-ANHVAFCRETQR 268
            .|...:|:.|   :..|:.:|....:...|..|.:.||..:    .|:..|: .|.....|..|.
Human   260 ESNNAQIKHENEQDMLKKQKAKQETRTILQKALQERIEHIQ----QEYRDEQDLNMKLVQRALQD 320

  Fly   269 LEAEALANIAQSKKDLNRATLEYLAYLRRMQSLELGIEKMMDERIADLYQLDMCTKVNITER-VR 332
            |:.|| ....|.::|:.|....|..||.:.:..|...||..|.    :.:.|...|:...:: :|
Human   321 LQEEA-DKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDR----ILEEDKAKKLAEKDKELR 380

  Fly   333 VKREAAEKCHEILRKQICED--------YERKIRSDAELRENKMMENRFVHPEVTH------EMI 383
            :::||        |:|:.::        .:.|::.:|:.:|.:.||.:.::..:..      |..
Human   381 LEKEA--------RRQLVDEVMCTRKLQVQEKLQREAKEQEERAMEQKHINESLKELNCEEKENF 437

  Fly   384 ACRQ---IQHKADLDAQIKEMKRIQEEEEKRFDSRLMAAVDDPVLCKRLAKEILDNGVDYLAP-- 443
            |.||   .:::..|..||...::.||.|::.......|.|....:|....:|:|  ....:.|
Human   438 ARRQRLAQEYRKQLQMQIAYQQQSQEAEKEEKRREFEAGVAANKMCLDKVQEVL--STHQVLPQN 500

  Fly   444 -HPNWRVMACNPNKYIP 459
             ||..:  || |:|..|
Human   501 IHPMRK--AC-PSKLPP 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34425	NP_001097683.1	PTZ00121	<29..402	CDD:173412	89/399 (22%)
CFAP53	NP_659457.2	TOP4c	<54..171	CDD:238111	27/101 (27%)
		TPH	130..451	CDD:290579	75/341 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52256
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR31183
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.110