DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-delta and KIRREL2

DIOPT Version :9

Sequence 1:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_954649.3 Gene:KIRREL2 / 84063 HGNCID:18816 Length:708 Species:Homo sapiens


Alignment Length:274 Identity:65/274 - (23%)
Similarity:102/274 - (37%) Gaps:56/274 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 PRFAQPIPNVTVAVGRDANLPCVVEHLGGY--KVAWIHIDRQMILTIHRHVISRIPRYSITYTDN 106
            |.|.|...::.|.:|.:|.|||.   ||.|  .|.|  ....:.|...|.    :|.:|     .
Human    24 PHFLQQPEDLVVLLGEEARLPCA---LGAYWGLVQW--TKSGLALGGQRD----LPGWS-----R 74

  Fly   107 TWL----------LHVNQAHQDDRGYYMCQVNTNPMISQVGYLQVVVPPNILDIESTPSSVAVRE 161
            .|:          ||:.....:|...|.||.....:.|:...|.|:|||....:...| ||::..
Human    75 YWISGNAANGQHDLHIRPVELEDEASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGP-SVSLVA 138

  Fly   162 NQNINMTCRA--DGFPAPKIIWRRE---------------DGEEIAVEKKKKVLVYDADVLPLTK 209
            ....|:|||:  |..|.|:::|.|:               :|...:||          ..|.||.
Human   139 GVPANLTCRSRGDARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVE----------STLTLTP 193

  Fly   210 VSRNEMGAYLCIA-TNGVPPSVSKRIILDVEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAII 273
            .|.::...::|.| :..:|......|.|.:::.|.:.:.........|..|...|...|.|....
Human   194 FSHDDGATFVCRARSQALPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFLCQATAQPPVTG 258

  Fly   274 Y-WVYNSVMVLPSK 286
            | |......||.::
Human   259 YRWAKGGSPVLGAR 272

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 25/103 (24%)
Ig 145..238 CDD:416386 25/110 (23%)
Ig strand A 145..149 CDD:409353 1/3 (33%)
Ig strand A' 154..159 CDD:409353 3/4 (75%)
Ig strand B 165..172 CDD:409353 4/8 (50%)
Ig strand C 178..183 CDD:409353 1/4 (25%)
Ig strand C' 185..187 CDD:409353 0/1 (0%)
Ig strand D 195..199 CDD:409353 0/3 (0%)
Ig strand E 203..209 CDD:409353 2/5 (40%)
Ig strand F 216..223 CDD:409353 2/7 (29%)
Ig strand G 230..238 CDD:409353 2/7 (29%)
Ig 242..333 CDD:416386 10/46 (22%)
Ig strand A' 250..253 CDD:409353 0/2 (0%)
Ig strand B 259..266 CDD:409353 2/6 (33%)
Ig strand C 272..277 CDD:409353 2/5 (40%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353
Ig strand E 295..305 CDD:409353
Ig strand F 314..322 CDD:409353
Ig strand G 325..334 CDD:409353
KIRREL2NP_954649.3 IG_like 30..119 CDD:214653 24/102 (24%)
IGc2 38..106 CDD:197706 21/81 (26%)
I-set 126..224 CDD:254352 24/108 (22%)
Ig2_KIRREL3-like 141..223 CDD:143236 21/91 (23%)
Cell attachment site. /evidence=ECO:0000255 149..151 0/1 (0%)
Ig 231..306 CDD:299845 9/42 (21%)
IG_like 234..308 CDD:214653 9/39 (23%)
Ig 312..395 CDD:299845
I-set 317..395 CDD:254352
Ig 397..501 CDD:299845
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 545..601
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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