DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-delta and Negr1

DIOPT Version :9

Sequence 1:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster
Sequence 2:XP_038958934.1 Gene:Negr1 / 59318 RGDID:708416 Length:362 Species:Rattus norvegicus


Alignment Length:324 Identity:94/324 - (29%)
Similarity:134/324 - (41%) Gaps:39/324 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 IPNVTVAVGRDANLPCVVEHLGGYKVAWIHIDRQMILTIHRHVISRIPRYSI-TYTDNTWLLHVN 113
            :.|:.|..|..|.|.|.:|. |..|.||  ::|..|:.......|..||.|| |.....:.|.:.
  Rat    39 VDNMLVRKGDTAVLRCYLED-GASKGAW--LNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQ 100

  Fly   114 QAHQDDRGYYMCQVNT--NPMISQVGYLQVVVPPNILDIESTPSSVAVRENQNINMTCRADGFPA 176
            .....|.|.|.|.|.|  .|...|| :|.|.|||.|.||.   :.:.:.|..|:.:||.|.|.|.
  Rat   101 NVDVTDDGPYTCSVQTQHTPRTMQV-HLTVQVPPKIYDIS---NDMTINEGTNVTLTCLATGKPE 161

  Fly   177 PKIIWRREDGEEIAVEKKKKVLVYDADVLPLTKVSRNEMGAYLCIATNGVP-PSVSK-RIILDVE 239
            |.|.||.........|..:.:.:|.        ::|::.|.|.|.|.|.|. |.|.| |::  |.
  Rat   162 PAISWRHISPSAKPFENGQYLDIYG--------ITRDQAGEYECSAENDVSFPDVKKVRVV--VN 216

  Fly   240 FSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIYW------VYNSVMVLPSKKYKTDYTENSYR 298
            |:|.|.........| |....|.|.....|.....|      ::|....:..:.:.|        
  Rat   217 FAPTIQEIKSGTVTP-GRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFST-------- 272

  Fly   299 AHMKLTIRNLQYGDFGNYRCISKNSLGETEGSIRVYEIPLPSTPSKQVTHTTVESRENNIIPSS 362
             ...||:.|:....||||.|::.|.||.|..|:.:.:|..|:| |..||.....:.:..|..|:
  Rat   273 -RSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNQIIEPTT-SSPVTSPAPSTAQYGITGSA 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 31/94 (33%)
Ig 145..238 CDD:416386 28/94 (30%)
Ig strand A 145..149 CDD:409353 2/3 (67%)
Ig strand A' 154..159 CDD:409353 0/4 (0%)
Ig strand B 165..172 CDD:409353 2/6 (33%)
Ig strand C 178..183 CDD:409353 2/4 (50%)
Ig strand C' 185..187 CDD:409353 0/1 (0%)
Ig strand D 195..199 CDD:409353 0/3 (0%)
Ig strand E 203..209 CDD:409353 0/5 (0%)
Ig strand F 216..223 CDD:409353 3/6 (50%)
Ig strand G 230..238 CDD:409353 3/8 (38%)
Ig 242..333 CDD:416386 23/96 (24%)
Ig strand A' 250..253 CDD:409353 0/2 (0%)
Ig strand B 259..266 CDD:409353 2/6 (33%)
Ig strand C 272..277 CDD:409353 1/10 (10%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353 1/3 (33%)
Ig strand E 295..305 CDD:409353 1/9 (11%)
Ig strand F 314..322 CDD:409353 4/7 (57%)
Ig strand G 325..334 CDD:409353 3/8 (38%)
Negr1XP_038958934.1 FR1 38..55 CDD:409353 5/15 (33%)
Ig strand A' 40..46 CDD:409353 2/5 (40%)
IG_like 41..129 CDD:214653 30/91 (33%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 1/4 (25%)
FR2 61..68 CDD:409353 3/8 (38%)
Ig strand C 61..67 CDD:409353 3/7 (43%)
CDR2 69..79 CDD:409353 1/9 (11%)
Ig strand C' 71..74 CDD:409353 1/2 (50%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 11/34 (32%)
Ig strand D 84..91 CDD:409353 4/6 (67%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 4/9 (44%)
FR4 122..129 CDD:409353 3/7 (43%)
Ig strand A' 139..144 CDD:409353 0/7 (0%)
IGc2 146..204 CDD:197706 19/65 (29%)
Ig strand B 150..157 CDD:409353 2/6 (33%)
Ig strand C 163..168 CDD:409353 2/4 (50%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 0/5 (0%)
Ig strand F 193..200 CDD:409353 3/6 (50%)
Ig strand G 207..215 CDD:409353 3/9 (33%)
Ig_3 219..295 CDD:404760 18/85 (21%)
putative Ig strand A 219..225 CDD:409353 2/5 (40%)
Ig strand B 235..239 CDD:409353 1/3 (33%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 3/4 (75%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 45 1.000 Domainoid score I11853
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4382
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8971
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
87.970

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