DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-delta and hmcn2

DIOPT Version :10

Sequence 1:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster
Sequence 2:XP_001920501.5 Gene:hmcn2 / 565032 ZFINID:ZDB-GENE-030131-9765 Length:4212 Species:Danio rerio


Alignment Length:557 Identity:119/557 - (21%)
Similarity:196/557 - (35%) Gaps:170/557 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 VTHVMMDEPRFAQPIPNVTVAVGRDANLPCVVEHLGGYKV---AWIHIDRQMILTIHRHVISRIP 97
            ||...::.|...|..|::|..:.:..||||.:  |.|..:   .|.|..:|:          |:.
Zfish   877 VTVTGLEPPLLVQGAPSITTMIAQPLNLPCRL--LDGIPLPERIWTHNGKQV----------RVG 929

  Fly    98 RYSITYTDNTWLLHVNQAHQDDRGYYMC-QVNTNPMISQVGYLQVVVPPNILDIESTPSSVAVRE 161
            ......:|.:  |||::|..:|.|.|:| .||.....:....::|..||   ||::.|......|
Zfish   930 GRVFLRSDGS--LHVDRAVPEDAGTYVCTAVNVAGSANITVTVEVHAPP---DIKAGPLHYTASE 989

  Fly   162 NQNINMTCRADGFPAPKIIWRR------------------------------------------- 183
            ...|:::|.|.|.|.|.|.|.:                                           
Zfish   990 GTPISLSCEARGVPKPTISWSKGRDPLNRPVSAPFEAADGSLYISSPTEEDAGVYICTATSAVGY 1054

  Fly   184 -----------------EDGEEIAVEKKKKV---LVYDADV----LPLTKVSRN----------- 213
                             .||.::.|:...:|   ::...:|    .||...|||           
Zfish  1055 TSREMHLIVNSKPRIVGADGSQVTVKMAAEVGSEVILPCEVQGSPTPLVTWSRNGQTIPPVTAWF 1119

  Fly   214 ----------------EMGAYLCIATNGVPPSVSKRIILDVEFSPMIWVPNQLVGAPSGTDVTID 262
                            :...|.|.|.|.. .:||....|.|:..|.|......:.|..|..|.:.
Zfish  1120 TMLPSGSLKISDVRVVDSKLYTCSAVNPA-GNVSLTYNLQVQAKPRIHPAPSTLKALIGQTVVLP 1183

  Fly   263 CHTEAHPKAIIYWVYNSVMVLPSKKYKTDYTENSYRAHMKLTIRNLQYGDFGNYRCISKNSLGET 327
            |..:..|...:.|::|.:.|...:..|               |:.:|:.|.|.|||:::||.||.
Zfish  1184 CVVQGEPSPQVSWLHNGLPVASDRMLK---------------IQAVQHSDSGTYRCVARNSAGED 1233

  Fly   328 EGSI--RVYEIPLPSTPSKQVTHTTVESRENN--IIP-SSRNDTTKSL------------QTDVG 375
            ...|  .|.|.|...|..:    |.:||..|:  :|| .:|......:            :::.|
Zfish  1234 TIQIVLDVLEGPYFETNGE----TVIESVANSKVLIPCPARGSPAPQVRWFKNGLEVHMERSEHG 1294

  Fly   376 YAMKND--LYPGSASSSSSGGSSSAASS-SSSMQTSA-----LPGGVA--GNSLS-SMGSKGSLA 429
            .::..|  |..||||:|.||.....|:: :.|::...     :|..:.  |..|: ::..|..|.
Zfish  1295 VSLAEDGALVIGSASASHSGDFKCVATNEAGSVERKTRLKVNVPPEIQDDGQLLNLTVTLKQPLT 1359

  Fly   430 IGKSTFYTERPPNEYAASSVAGLLLHRALLFGSGIYL 466
            :|...|....|...:...       :|.:|...|:||
Zfish  1360 LGCDAFGIPTPTISWTKD-------NRPVLETPGVYL 1389

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-deltaNP_001097508.2 IG_like 51..143 CDD:214653 24/95 (25%)
Ig strand B 61..65 CDD:409353 2/3 (67%)
Ig strand C 74..78 CDD:409353 0/6 (0%)
Ig strand E 105..112 CDD:409353 2/6 (33%)
Ig strand F 122..127 CDD:409353 2/5 (40%)
Ig strand G 134..137 CDD:409353 0/2 (0%)
Ig 145..238 CDD:472250 30/186 (16%)
Ig strand B 165..169 CDD:409353 1/3 (33%)
Ig strand C 178..182 CDD:409353 1/3 (33%)
Ig strand E 203..207 CDD:409353 1/7 (14%)
Ig strand F 217..222 CDD:409353 2/4 (50%)
Ig strand G 231..234 CDD:409353 1/2 (50%)
Ig 242..333 CDD:472250 23/92 (25%)
Ig strand B 259..263 CDD:409353 1/3 (33%)
Ig strand C 272..276 CDD:409353 0/3 (0%)
Ig strand E 295..305 CDD:409353 0/9 (0%)
Ig strand F 315..320 CDD:409353 3/4 (75%)
Ig strand G 328..331 CDD:409353 0/2 (0%)
hmcn2XP_001920501.5 Ig strand F 1221..1226 CDD:409570 3/4 (75%)
Ig strand G 1234..1237 CDD:409570 0/2 (0%)
Ig 1245..1335 CDD:472250 21/93 (23%)
Ig strand B 1263..1267 CDD:409570 1/3 (33%)
Ig strand C 1276..1280 CDD:409570 0/3 (0%)
Ig strand E 1301..1305 CDD:409570 1/3 (33%)
Ig strand F 1315..1320 CDD:409570 0/4 (0%)
Ig strand G 1328..1331 CDD:409570 0/2 (0%)
Ig 1338..1430 CDD:472250 13/59 (22%)
Ig strand B 1358..1362 CDD:409353 1/3 (33%)
Ig strand C 1371..1375 CDD:409353 0/3 (0%)
Ig strand E 1394..1398 CDD:409353
Ig strand F 1408..1413 CDD:409353
Ig strand G 1421..1424 CDD:409353
I-set 1443..1523 CDD:400151
Ig strand B 1451..1455 CDD:409353
Ig strand C 1464..1468 CDD:409353
Ig strand E 1488..1493 CDD:409353
Ig strand F 1503..1508 CDD:409353
I-set 1538..1608 CDD:400151
Ig strand B 1546..1550 CDD:409353
Ig strand C 1559..1563 CDD:409353
Ig strand E 1582..1586 CDD:409353
Ig strand F 1596..1601 CDD:409353
Ig strand G 1610..1613 CDD:409353
ChlD <21..206 CDD:440853
IG_like 441..512 CDD:214653
Ig 516..603 CDD:472250
Ig strand B 533..537 CDD:409353
Ig strand C 546..550 CDD:409353
Ig strand E 569..573 CDD:409353
Ig strand F 583..588 CDD:409353
Ig strand G 596..599 CDD:409353
Ig_3 607..680 CDD:464046
I-set 711..784 CDD:400151
Ig strand B 714..718 CDD:409353
Ig strand C 727..731 CDD:409353
Ig strand E 750..754 CDD:409353
Ig strand F 764..769 CDD:409353
Ig strand G 777..780 CDD:409353
IG_like 794..879 CDD:214653 1/1 (100%)
Ig strand B 805..809 CDD:409353
Ig strand C 818..822 CDD:409353
Ig strand E 845..849 CDD:409353
Ig strand F 859..864 CDD:409353
Ig strand G 872..875 CDD:409353
Ig 885..972 CDD:472250 25/100 (25%)
Ig strand C 916..920 CDD:409353 0/3 (0%)
Ig strand E 938..942 CDD:409353 1/5 (20%)
Ig strand F 952..957 CDD:409353 2/4 (50%)
Ig strand G 965..968 CDD:409353 0/2 (0%)
Ig_3 975..1049 CDD:464046 14/76 (18%)
IG_like 1083..1159 CDD:214653 14/76 (18%)
Ig strand B 1089..1093 CDD:409353 0/3 (0%)
Ig strand C 1102..1106 CDD:409353 1/3 (33%)
Ig strand E 1125..1129 CDD:409353 0/3 (0%)
Ig strand F 1139..1144 CDD:409353 2/4 (50%)
Ig strand G 1152..1155 CDD:409353 1/2 (50%)
I-set 1163..1241 CDD:400151 23/92 (25%)
Ig strand B 1180..1184 CDD:409570 1/3 (33%)
Ig strand C 1193..1197 CDD:409570 0/3 (0%)
Ig strand E 1208..1211 CDD:409570 1/17 (6%)
Ig 1637..1714 CDD:472250
Ig strand B 1644..1648 CDD:409353
Ig strand C 1657..1661 CDD:409353
Ig strand E 1680..1684 CDD:409353
Ig strand F 1694..1699 CDD:409353
IG_like 1753..1830 CDD:214653
Ig strand B 1760..1764 CDD:409353
Ig strand C 1773..1777 CDD:409353
Ig strand E 1796..1800 CDD:409353
Ig strand F 1810..1815 CDD:409353
Ig strand G 1823..1826 CDD:409353
I-set 1834..1918 CDD:400151
Ig strand B 1855..1859 CDD:409256
Ig strand C 1868..1872 CDD:409256
Ig strand E 1891..1895 CDD:409256
Ig strand F 1905..1910 CDD:409256
Ig strand G 1918..1921 CDD:409256
Ig 1939..2017 CDD:472250
Ig strand B 1947..1951 CDD:409256
Ig strand C 1960..1964 CDD:409256
Ig strand E 1983..1987 CDD:409256
Ig strand F 1997..2002 CDD:409256
Ig strand G 2010..2013 CDD:409256
I-set 2038..2110 CDD:400151
Ig strand B 2042..2046 CDD:409353
Ig strand C 2055..2059 CDD:409353
Ig strand F 2090..2095 CDD:409353
Ig_3 2113..2189 CDD:464046
Ig_3 2205..2282 CDD:464046
I-set 2307..2391 CDD:400151
Ig strand B 2321..2325 CDD:409353
Ig strand C 2334..2338 CDD:409353
Ig strand E 2357..2361 CDD:409353
Ig strand F 2371..2376 CDD:409353
I-set 2400..2484 CDD:400151
Ig strand B 2414..2418 CDD:409353
Ig strand C 2427..2431 CDD:409353
Ig strand E 2447..2454 CDD:409353
Ig strand F 2464..2469 CDD:409353
Ig_3 2487..2562 CDD:464046
Ig 2599..2667 CDD:472250
Ig strand B 2599..2603 CDD:409353
Ig strand C 2612..2616 CDD:409353
Ig strand E 2635..2639 CDD:409353
Ig strand F 2649..2654 CDD:409353
IG_like 2679..2760 CDD:214653
Ig strand B 2690..2694 CDD:409353
Ig strand C 2703..2707 CDD:409353
Ig strand E 2726..2730 CDD:409353
Ig strand F 2740..2745 CDD:409353
Ig_3 2764..2839 CDD:464046
Ig 2857..2943 CDD:472250
Ig strand B 2873..2877 CDD:409353
Ig strand C 2886..2890 CDD:409353
Ig strand E 2909..2913 CDD:409353
Ig strand F 2923..2928 CDD:409353
Ig strand G 2936..2939 CDD:409353
Ig_3 2946..3020 CDD:464046
Ig_3 3036..3110 CDD:464046
IG_like 3133..3214 CDD:214653
Ig strand B 3144..3148 CDD:409353
Ig strand C 3157..3161 CDD:409353
Ig strand E 3180..3184 CDD:409353
Ig strand F 3194..3199 CDD:409353
Ig strand G 3207..3210 CDD:409353
Ig 3218..3293 CDD:472250
Ig strand B 3235..3239 CDD:409353
Ig strand C 3248..3252 CDD:409353
Ig strand E 3269..3273 CDD:409353
Ig strand F 3283..3288 CDD:409353
I-set 3316..3394 CDD:400151
Ig strand B 3325..3329 CDD:409353
Ig strand C 3338..3342 CDD:409353
Ig strand E 3360..3364 CDD:409353
Ig strand F 3374..3379 CDD:409353
Ig strand G 3387..3390 CDD:409353
TSP1 3401..3452 CDD:214559
G2F 3454..3636 CDD:462175
EGF_CA 3691..3721 CDD:214542
EGF_CA 3731..3775 CDD:214542
EGF_CA 3776..3814 CDD:214542
EGF_CA 3816..3849 CDD:238011
EGF_CA 3858..3889 CDD:429571
EGF_CA 3901..3940 CDD:214542
EGF_CA 4005..4044 CDD:214542
EGF_CA 4045..4085 CDD:214542
Blue background indicates that the domain is not in the aligned region.

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