Protein Alignment DIP-delta and OPCML

DIOPT Version :10

• Sequence 1: NP_001097508.2
• Gene: DIP-delta / 5740816
• FlyBaseID: FBgn0085420
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001306032.1
• Gene: OPCML / 4978
• HGNCID: 8143
• Length: 354
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 96/328 - (29%)
• Similarity: 146/328 - (44%)
• Gaps: 33/328 - (10%)

  Fly    25 RIMFLIYMTNLVTHVMMDEPRFAQPIPNVTVAVGRDANLPCVVEHLGGYKVAWIHIDRQMILTIH 89
            |::||: .|.:  .|...:..|.:.:.||||..|..|.|.|.::. ...:|||  ::|..||...
Human    20 RLLFLV-PTGV--PVRSGDATFPKAMDNVTVRQGESATLRCTIDD-RVTRVAW--LNRSTILYAG 78

  Fly    90 RHVISRIPRYSI-TYTDNTWLLHVNQAHQDDRGYYMCQVNT--NPMISQVGYLQVVVPPNILDIE 151
            ....|..||..| ..|...:.:.:......|.|.|.|.|.|  :|..|:| :|.|.|||.|::|.
Human    79 NDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRV-HLIVQVPPQIMNIS 142

  Fly   152 STPSSVAVRENQNINMTCRADGFPAPKIIWRREDGEEIAVEKKKKVLVYDADVLPLTKVSRNEMG 216
               |.:.|.|..::.:.|.|.|.|.|.:.||     .::| |:.:..|.:.:.|.::.:.|::.|
Human   143 ---SDITVNEGSSVTLLCLAIGRPEPTVTWR-----HLSV-KEGQGFVSEDEYLEISDIKRDQSG 198

  Fly   217 AYLCIATNGVPPSVSKRIILDVEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIYWVYNSVM 281
            .|.|.|.|.|.....:::.:.|.:.|.|..... .|...|....:.|...|.|.|...|......
Human   199 EYECSALNDVAAPDVRKVKITVNYPPYISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETR 262

  Fly   282 V---LPSKKYKTDYTENSYRAHMKLTIRNLQYGDFGNYRCISKNSLGETEGSIRVYEIPLPSTPS 343
            :   |...:     .||..|. ..||..|:...|:|||.|::.|.||.|..||.:|||    :||
Human   263 LATGLDGMR-----IENKGRM-STLTFFNVSEKDYGNYTCVATNKLGNTNASITLYEI----SPS 317

  Fly   344 KQV 346
            ..|
Human   318 SAV 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-delta	NP_001097508.2	IG_like	51..143	CDD:214653	30/94 (32%)
		Ig strand B	61..65	CDD:409353	2/3 (67%)
		Ig strand C	74..78	CDD:409353	2/3 (67%)
		Ig strand E	105..112	CDD:409353	0/6 (0%)
		Ig strand F	122..127	CDD:409353	2/4 (50%)
		Ig strand G	134..137	CDD:409353	1/2 (50%)
		Ig	145..238	CDD:472250	24/92 (26%)
		Ig strand B	165..169	CDD:409353	0/3 (0%)
		Ig strand C	178..182	CDD:409353	0/3 (0%)
		Ig strand E	203..207	CDD:409353	1/3 (33%)
		Ig strand F	217..222	CDD:409353	2/4 (50%)
		Ig strand G	231..234	CDD:409353	0/2 (0%)
		Ig	242..333	CDD:472250	27/93 (29%)
		Ig strand B	259..263	CDD:409353	0/3 (0%)
		Ig strand C	272..276	CDD:409353	0/3 (0%)
		Ig strand E	295..305	CDD:409353	3/9 (33%)
		Ig strand F	315..320	CDD:409353	3/4 (75%)
		Ig strand G	328..331	CDD:409353	0/2 (0%)
OPCML	NP_001306032.1	Ig	44..132	CDD:472250	29/91 (32%)
		Ig strand B	53..57	CDD:409353	2/3 (67%)
		Ig strand C	65..69	CDD:409353	3/5 (60%)
		Ig strand E	98..102	CDD:409353	0/3 (0%)
		Ig strand F	112..117	CDD:409353	2/4 (50%)
		Ig strand G	125..128	CDD:409353	1/2 (50%)
		Ig_3	135..206	CDD:464046	23/79 (29%)
		Ig	224..312	CDD:472250	27/94 (29%)
		Ig strand B	240..244	CDD:409353	0/3 (0%)
		Ig strand C	253..257	CDD:409353	0/3 (0%)
		Ig strand E	279..283	CDD:409353	1/3 (33%)
		Ig strand F	293..298	CDD:409353	3/4 (75%)
		Ig strand G	306..309	CDD:409353	0/2 (0%)