DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-delta and Dscam2

DIOPT Version :9

Sequence 1:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster


Alignment Length:566 Identity:134/566 - (23%)
Similarity:194/566 - (34%) Gaps:180/566 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 TNRRIMFLIYMT---------NLVTHVMMD---------EPR----------------FAQPIPN 52
            :|.|.|...|:|         | ::|||::         |.|                :.:.||.
  Fly   465 SNGRFMIGQYITVHGDVISHVN-ISHVMVEDGGEYACIAENRAGRVQHAARLNIYGLPYIRLIPK 528

  Fly    53 VTVAVGRDANLPCVVEHLGGYKVAWIHID----------RQMI-----LTI-------------- 88
            ||...|...||.|.|   .||.:..||.:          ||.:     |||              
  Fly   529 VTAVSGETLNLKCPV---AGYPIEEIHWERGGRELPDDIRQRVQPDGSLTISPVQKNSDSGVYTC 590

  Fly    89 -----HRHVISR-------IP-----------------RYSITYT-------------------D 105
                 ..|...|       :|                 |.|:|.:                   |
  Fly   591 WARNKQGHSARRSGEVTVIVPPKLSPFQTNILQLNMGDRASLTCSVVKGDLPLTINWRKDGRPID 655

  Fly   106 NTWLLHVNQAHQ------------DDRGYYMCQV-NTNPMISQVGYLQVVVPPNILDIESTPSSV 157
            .|..:.|.|..|            |..|.|.|.| |:...:.....|.|.|||..: :|  |...
  Fly   656 PTQHMSVKQVDQYNSILVIENLGSDHTGNYSCVVRNSAAEVENSQALLVNVPPRWI-VE--PVDA 717

  Fly   158 AVRENQNINMTCRADGFPAPKIIWRREDG------EEIAVEKKKKVLVYDADVLPLTKVSRNEMG 216
            .|..|::|.:.|:|.|.|.|.|:|::..|      ||:......|:|...:  |.|..|..:..|
  Fly   718 NVERNRHIMLHCQAQGVPTPSIVWKKATGSKSGEYEEVRERPFTKLLGNGS--LLLQHVKEDREG 780

  Fly   217 AYLCIATNGVPPSVSKRIILDVEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIYWVYNSVM 281
            .|||.|.||:...:.|.|.|.|..||.....::.|....|....:.|.........|.|:.:...
  Fly   781 FYLCQANNGIGTGIGKVIQLKVNSSPYFSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSGKN 845

  Fly   282 VL-PSKKY----KTDYTENSYRAHMKLTIRNLQYGDFGNYRCISKNSLGETEG--SIRVYEIPLP 339
            .| ||..|    |.:.|.:...|  :|.||.:...|.|.|.|.:.|..|..:.  .::|.|.|||
  Fly   846 TLNPSTNYKISVKQEATPDGVSA--ELQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQEPPLP 908

  Fly   340 STPS-----------------------KQVTHTTVESRE--NNIIPSSRNDTTKSLQT-DVGY-- 376
              ||                       ..||...||.||  :::.|:...|..:.::. |..:  
  Fly   909 --PSVLEAAMISSRSVNIKWQPKTLGTGDVTKYIVEFREADHSLPPALFVDQWQQIEVKDPPHFN 971

  Fly   377 AMKNDLYPGS--ASSSSSGGSSSAASSSSSMQTSALPGGVAGNSLS 420
            ||..:|.|.:  |....:.||:..::.|..:.....|...||..||
  Fly   972 AMIENLKPATRYAFRVIAEGSAGRSAPSQELIVRTEPQRPAGPPLS 1017

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 36/181 (20%)
Ig 145..238 CDD:416386 31/98 (32%)
Ig strand A 145..149 CDD:409353 1/3 (33%)
Ig strand A' 154..159 CDD:409353 1/4 (25%)
Ig strand B 165..172 CDD:409353 2/6 (33%)
Ig strand C 178..183 CDD:409353 2/4 (50%)
Ig strand C' 185..187 CDD:409353 1/7 (14%)
Ig strand D 195..199 CDD:409353 1/3 (33%)
Ig strand E 203..209 CDD:409353 2/5 (40%)
Ig strand F 216..223 CDD:409353 4/6 (67%)
Ig strand G 230..238 CDD:409353 3/7 (43%)
Ig 242..333 CDD:416386 22/97 (23%)
Ig strand A' 250..253 CDD:409353 1/2 (50%)
Ig strand B 259..266 CDD:409353 1/6 (17%)
Ig strand C 272..277 CDD:409353 2/4 (50%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353 1/3 (33%)
Ig strand E 295..305 CDD:409353 2/9 (22%)
Ig strand F 314..322 CDD:409353 3/7 (43%)
Ig strand G 325..334 CDD:409353 1/10 (10%)
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352
Ig 247..327 CDD:299845
I-set 332..418 CDD:254352
IGc2 344..407 CDD:197706
IG_like 432..517 CDD:214653 11/52 (21%)
IGc2 436..507 CDD:197706 11/42 (26%)
I-set 521..610 CDD:254352 20/91 (22%)
IGc2 533..597 CDD:197706 14/66 (21%)
Ig 630..699 CDD:143165 13/68 (19%)
IG_like 714..802 CDD:214653 29/89 (33%)
Ig 725..802 CDD:299845 26/78 (33%)
Ig 823..894 CDD:143165 19/72 (26%)
FN3 906..1006 CDD:238020 22/101 (22%)
FN3 1013..1111 CDD:238020 3/5 (60%)
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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