DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-delta and dpr19

DIOPT Version :9

Sequence 1:	NP_001097508.2	Gene:	DIP-delta / 5740816	FlyBaseID:	FBgn0085420	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster

Alignment Length:	371	Identity:	83/371 - (22%)
Similarity:	141/371 - (38%)	Gaps:	81/371 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 PSRFTNRRIMFLIYMTNL---VTHVMMDEPRFAQPIPN---------VTVAVGRDANLPCVVEHL 70
            |.|:......||:.:::.   |..:...:..|...:.:         |....|..|.|||||:..
  Fly     3 PKRWHLHLSCFLLLLSSTFSDVGKITSSQNHFGNTLQSQFNTKNNTRVIAQKGGLAILPCVVKVN 67

  Fly    71 GGYKVAWIHIDRQMILTIHRHVISRIPRYSITYTDNT--WLLHVNQAHQDDRGYYMCQVNTNPMI 133
            ....|:||......:||:.....|...|:.:.:|.:.  |.|.:....::|||:|.||::..|..
  Fly    68 SPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQLSIYPTQ 132

  Fly   134 SQVGYLQVVVPPNILDIESTPSSVAVRENQNINMTC---RADGFPAPKIIWRREDGEEIAVEKKK 195
            |.|..|::|  ..:.:|.|.| .:.:.|...:.:.|   ||...|| .:.|..:          .
  Fly   133 SIVIELKIV--EAVAEISSAP-ELHIDETSTLRLECKLKRATENPA-FVFWYHD----------S 183

  Fly   196 KVLVYDAD---VLPLTKVSRNEMGAYLCIATNGVPPSVSKRIILDVEFSPMIWVPNQLVGA---- 253
            |::.||:.   |:.....|..:.|.:...:     |:...|..:.:|.|.  .|.|.|:|:
  Fly   184 KMINYDSQGGFVVTSIGQSNPQSGQFYRSS-----PANKSRATMPMESSN--GVLNSLLGSSDAI 241

  Fly   254 -------PSGTDVTIDCHTEAHPKAIIYWVYNSVMVLPSKKYKTDYTENSYRAHMKLTIRNLQYG 311
                   ||.|...    |:.|..|  |.:..||.|                    ||::.:.:.
  Fly   242 KAPAANVPSSTPYM----TQQHQSA--YLLNPSVSV--------------------LTVKQVNFR 280

  Fly   312 DFGNYRCISKNSLGETEGSIRVYEIPLPSTPSKQVTHTTVESRENN 357
            ..|||.|...|:   ...||.|:.:....|.:.|..:.::...|.|
  Fly   281 HAGNYTCAPSNA---RPASITVHVLRGEKTAAMQHANRSILDTETN 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-delta	NP_001097508.2	IG	51..143	CDD:214652	28/102 (27%)
		Ig	145..238	CDD:416386	18/98 (18%)
		Ig strand A	145..149	CDD:409353	0/3 (0%)
		Ig strand A'	154..159	CDD:409353	1/4 (25%)
		Ig strand B	165..172	CDD:409353	2/9 (22%)
		Ig strand C	178..183	CDD:409353	1/4 (25%)
		Ig strand C'	185..187	CDD:409353	0/1 (0%)
		Ig strand D	195..199	CDD:409353	1/3 (33%)
		Ig strand E	203..209	CDD:409353	1/8 (13%)
		Ig strand F	216..223	CDD:409353	1/6 (17%)
		Ig strand G	230..238	CDD:409353	1/7 (14%)
		Ig	242..333	CDD:416386	23/101 (23%)
		Ig strand A'	250..253	CDD:409353	1/2 (50%)
		Ig strand B	259..266	CDD:409353	0/6 (0%)
		Ig strand C	272..277	CDD:409353	1/4 (25%)
		Ig strand C'	281..283	CDD:409353	0/1 (0%)
		Ig strand D	289..293	CDD:409353	0/3 (0%)
		Ig strand E	295..305	CDD:409353	1/9 (11%)
		Ig strand F	314..322	CDD:409353	4/7 (57%)
		Ig strand G	325..334	CDD:409353	2/8 (25%)
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	24/76 (32%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	21/69 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810