DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-delta and Lrit3

DIOPT Version :9

Sequence 1:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001274153.1 Gene:Lrit3 / 242235 MGIID:2685267 Length:681 Species:Mus musculus


Alignment Length:394 Identity:75/394 - (19%)
Similarity:139/394 - (35%) Gaps:120/394 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 LTIHRHVISRIPRYSITYTDNTWLLHVNQAHQDDRGYYMCQVNTNPMISQVGYLQVVVPPNILD- 149
            |.:|.:.|:.:|..::.|..|...|               .:::|.:        ..:||:.|| 
Mouse   134 LDLHNNRIASVPNEAVRYLRNLTCL---------------DLSSNRL--------TTLPPDFLDS
 175

  Fly   150 ---IESTPSSVAVRENQNINMTCRADGFPAPKIIWRREDGE---EIAVEKKKKVLVYDADVLPLT 208
               :..|||              |:..||..:||...:|..   :..:.|          |:.|:
Mouse   176 WSHLAVTPS--------------RSPDFPPRRIILGLQDNPWFCDCHISK----------VIELS 216

  Fly   209 KVSRNEM----GAYLCIATNGVPPSVSKRIILDVEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHP 269
            ||:.:.:    ...:|.........:.:|:.|:....|.:.:....:.:..|::|.:.|..:.||
Mouse   217 KVTDHAVVLLDPLMVCSEPERFQGILFQRVELEKCLKPSVMMSATKITSALGSNVLLRCDAKGHP 281

  Fly   270 KAIIYWV--------YNSVMVLPSKKYKTDYTENSYRAHMKLTIRNLQYGDFGNYRCISKNSLGE 326
            ...:.|.        |..:...|.:..:...          :::.::.:.|.|:|||.:||..|.
Mouse   282 TPQLTWTRSDGSTVNYTVIQESPGEGIRWSI----------ISLTSISHKDAGDYRCKAKNLAGI 336

  Fly   327 TEGSIRVYEI-PLPSTPSKQVTHTTV-ESRENNIIPSSRNDTTKSLQTDVGYAMKNDLYPGSASS 389
            :|..:.|..: .:.:|.|...:..:. |..|.:..|.....|..|         |:.|.||..|:
Mouse   337 SEAVVTVTVVGGVTTTLSPDSSERSPGEPPEQHPQPGLGGSTPPS---------KSWLSPGLTSA 392

  Fly   390 SSSGGSS-------------------SAASSSSSMQTSAL--------------PGGVAGNSLSS 421
            .|....|                   ||||:::|:|||..              |||.:...:..
Mouse   393 PSYPTPSAALYTSTWSPPPSSLPPIFSAASATTSVQTSISGRTARTSHQPPLLHPGGKSNAKIEK 457

  Fly   422 MGSK 425
            .|.|
Mouse   458 NGRK 461

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 8/56 (14%)
Ig 145..238 CDD:416386 20/103 (19%)
Ig strand A 145..149 CDD:409353 1/3 (33%)
Ig strand A' 154..159 CDD:409353 2/4 (50%)
Ig strand B 165..172 CDD:409353 1/6 (17%)
Ig strand C 178..183 CDD:409353 2/4 (50%)
Ig strand C' 185..187 CDD:409353 1/1 (100%)
Ig strand D 195..199 CDD:409353 0/3 (0%)
Ig strand E 203..209 CDD:409353 2/5 (40%)
Ig strand F 216..223 CDD:409353 1/6 (17%)
Ig strand G 230..238 CDD:409353 2/7 (29%)
Ig 242..333 CDD:416386 18/98 (18%)
Ig strand A' 250..253 CDD:409353 0/2 (0%)
Ig strand B 259..266 CDD:409353 2/6 (33%)
Ig strand C 272..277 CDD:409353 1/12 (8%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353 0/3 (0%)
Ig strand E 295..305 CDD:409353 0/9 (0%)
Ig strand F 314..322 CDD:409353 4/7 (57%)
Ig strand G 325..334 CDD:409353 2/8 (25%)
Lrit3NP_001274153.1 LRR 1. /evidence=ECO:0000255 56..79
LRR_8 61..117 CDD:290566
LRR 2. /evidence=ECO:0000255 80..103
leucine-rich repeat 83..106 CDD:275378
LRR 3. /evidence=ECO:0000255 104..128
LRR_8 105..165 CDD:290566 8/45 (18%)
LRR_4 106..146 CDD:289563 3/11 (27%)
leucine-rich repeat 107..130 CDD:275378
LRR_4 129..170 CDD:289563 8/58 (14%)
LRR 4. /evidence=ECO:0000255 129..151 4/16 (25%)
leucine-rich repeat 131..154 CDD:275378 5/19 (26%)
LRR 5. /evidence=ECO:0000255 152..175 6/45 (13%)
leucine-rich repeat 155..168 CDD:275378 2/35 (6%)
Ig 254..335 CDD:299845 16/90 (18%)
IG_like 263..339 CDD:214653 16/85 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 350..391 11/49 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 425..464 9/37 (24%)
FN3 489..563 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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