DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-delta and Lrit1

DIOPT Version :9

Sequence 1:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_666357.2 Gene:Lrit1 / 239037 MGIID:2385320 Length:624 Species:Mus musculus


Alignment Length:366 Identity:74/366 - (20%)
Similarity:126/366 - (34%) Gaps:114/366 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 WIHIDRQMILTIHRHVISRIPRYSITYTDNTWLLHVNQAHQDDRGYYMCQVNTNPMISQVGYLQV 141
            |.|:.....|:.|.      .|..:...||.|:.       |.|.|.:           |..|..
Mouse   178 WAHLKTGPFLSGHH------ARLILGLQDNPWVC-------DCRLYDL-----------VHLLDG 218

  Fly   142 VVPPNILDIE-----STPSSVA--------VRENQN-----------------INMTCRADGFPA 176
            .|..|::.||     ::|.|:|        :|:.|:                 :.:.|.|.|.|.
Mouse   219 WVSSNLIFIEARLRCASPRSLAG
VAFSQLELRKCQSPELRPGVTSIISPLGSTVLLRCGATGIPG 283

  Fly   177 PKIIWRREDG--------EEIAVEKKKKVLVYDADVLPLTKVSRNEMGAYLCIATNGVPPSVSKR 233
            |::.|||.:|        :|::.:.....|      |.|..||..:.|.|:|.|.|.:  ..|:.
Mouse   284 PEMSWRRANGRPLNGTVHQEVSSDGSSWTL------LDLPVVSLFDSGDYICQAKNFL--GASET 340

  Fly   234 IILDVEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIYWVYNSVMVLPSKKYKTDYTENSYR 298
            :|     |.::..|....|. ||....:...|....:|.   .||:.:|.....:..::...:.:
Mouse   341 LI-----SLIV
TEPQTSTGY-SGIPGVLWARTGEGAEAA---AYNNKLVARHVPHMPEHVALATK 396

  Fly   299 AHM-----KLTIRNLQY---GDFGN--------YRCISKNSLGETEGSIR-VYEIPLPSTPSKQV 346
            ..|     :|.::|.|.   |:|..        ....|...:|:|..|:. |::.|       |.
Mouse   397 PSMPSIKEELALQNFQMDVPGEFSREPSEHQEAQMVRSLKVVGDTYHSVSLVWKAP-------QA 454

  Fly   347 THTTV-----------ESRENNIIPSSRNDTTKSLQTDVGY 376
            .:||.           :.|...:.|...:.|.:.|.....|
Mouse   455 GNTTAFSVLYAVFGHRDMRRMTVEPGKTSVTIEGLAPKTKY 495

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 13/65 (20%)
Ig 145..238 CDD:416386 30/130 (23%)
Ig strand A 145..149 CDD:409353 1/3 (33%)
Ig strand A' 154..159 CDD:409353 3/12 (25%)
Ig strand B 165..172 CDD:409353 1/6 (17%)
Ig strand C 178..183 CDD:409353 1/4 (25%)
Ig strand C' 185..187 CDD:409353 1/9 (11%)
Ig strand D 195..199 CDD:409353 0/3 (0%)
Ig strand E 203..209 CDD:409353 2/5 (40%)
Ig strand F 216..223 CDD:409353 3/6 (50%)
Ig strand G 230..238 CDD:409353 2/7 (29%)
Ig 242..333 CDD:416386 19/107 (18%)
Ig strand A' 250..253 CDD:409353 0/2 (0%)
Ig strand B 259..266 CDD:409353 0/6 (0%)
Ig strand C 272..277 CDD:409353 0/4 (0%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353 0/3 (0%)
Ig strand E 295..305 CDD:409353 2/14 (14%)
Ig strand F 314..322 CDD:409353 1/15 (7%)
Ig strand G 325..334 CDD:409353 3/9 (33%)
Lrit1NP_666357.2 LRRNT 23..61 CDD:214470
LRR 1 60..81
LRR_8 63..143 CDD:290566
leucine-rich repeat 64..84 CDD:275378
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..>176 CDD:290566
LRR_4 131..172 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378 1/1 (100%)
leucine-rich repeat 181..205 CDD:275378 6/29 (21%)
TPKR_C2 201..>241 CDD:301599 13/57 (23%)
Ig 258..346 CDD:299845 23/100 (23%)
IG_like 268..346 CDD:214653 23/90 (26%)
FN3 432..502 CDD:214495 14/71 (20%)
LRR 6 526..549
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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